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Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Liu,Jie;  Yang,Shuo;  Cao,Bihui;  Zhou,Guangyu;  Zhang,Fengjuan;  Wang,Yuan;  Wang,Rixin;  Zhu,Lipeng;  Meng,Ya;  Hu,Cong;  Liang,Hui;  Lin,Xu;  Zhu,Kangshun;  Chen,Guokai;  Luo,Kathy Qian;  Di,Lijun;  Zhao,Qi
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/04
B7-h3  Bike  Bispecific Antibody  Car t  Chimeric Antigen Receptor  Non-small Cell Lung Cancer  Pd-l1  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatorial Science, 2018,Volume: 20,Issue: 11,Page: 660-671
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2018/12/18
cancer  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  Warburg effect  
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
JOURNAL OF PROTEOME RESEARCH, 2018,Volume: 17,Issue: 9,Page: 3012-3021
Authors:  Zhang, Wen;  Hu, Xiaohui;  Zhou, Wei;  Tam, Kin Yip
Favorite |  | TC[WOS]:7 TC[Scopus]:6 | Submit date:2018/10/30
Aerobic Glycolysis  Azd7545  Dichloroacetate  Lc-ms/ms  Pyruvate Dehydrogenase Kinases  Cancer Metabolism  
NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth Journal article
Cancer Letters, 2015,Volume: 359,Issue: 1,Page: 97-106
Authors:  Zha X.;  Hu Z.;  Ji S.;  Jin F.;  Jiang K.;  Li C.;  Zhao P.;  Tu Z.;  Chen X.;  Di L.;  Zhou H.;  Zhang H.
Favorite |  | TC[WOS]:34 TC[Scopus]:34 | Submit date:2018/12/21
Aerobic Glycolysis  Glut3  Mtor  Nfκb  Tumorigenesis  
Targeting tumor metabolism for cancer treatment: Is pyruvate dehydrogenase kinases (PDKs) a viable anticancer target? Journal article
International Journal of Biological Sciences, 2015,Volume: 11,Issue: 12,Page: 1390-1400
Authors:  Wen Zhang;  Shao-Lin Zhang;  Xiaohui Hu;  Kin Yip Tam
Favorite |  | TC[WOS]:78 TC[Scopus]:80 | Submit date:2019/01/07
Aerobic Glycolysis  Pyruvate Dehydrogenase Kinases  Tumor Metabolism  Pyruvate Dehydrogenase Complex