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Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:  Ren,Zhili;  Zhong,Hui;  Song,Chengcheng;  Deng,Chunhao;  Hsieh,Hsun Ting;  Liu,Weiwei;  Chen,Guokai
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Akt  Caspase  Cell Survival  Gsk3  Human Embryonic Stem Cells  Insulin  Mitochondrial Respiration  
The role of autophagy in liver cancer: Crosstalk in signaling pathways and potential therapeutic targets Journal article
Pharmaceuticals, 2020,Volume: 13,Issue: 12,Page: 1-27
Authors:  Cui,Jianzhou;  Shen,Han Ming;  Lim,Lina Hsiu Kim
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AMPK  Autophagy  HCC  MAPK  MTOR  P53  ULK1  
Mechanism Study of the Protective Effects of Sodium Tanshinone IIA Sulfonate Against Atorvastatin-Induced Cerebral Hemorrhage in Zebrafish: Transcriptome Analysis Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Zhou,Zhong Yan;  Zhao,Wai Rong;  Xiao,Ying;  Zhang,Jing;  Tang,Jing Yi;  Lee,Simon Ming Yuen
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atorvastatin  carbonic anhydrase  cerebral hemorrhage  hemoglobin  hypoxia-inducible factor 1  Na+/H+ exchanger  sodium tanshinone IIA sulfonate  traditional Chinese medicine  
Artemisinin protects motoneurons against axotomy-induced apoptosis through activation of the PKA-Akt signaling pathway and promotes neural stem/progenitor cells differentiation into NeuN+ neurons Journal article
Pharmacological Research, 2020,Volume: 159
Authors:  Liu,Linlin;  Zhao,Xia;  Silva,Marta;  Li,Shuai;  Xing,Xingan;  Zheng,Wenhua
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Artemisinin  Brachial plexus axotomy  Inflammatory response  Motoneurons  
Dolichosin A, a coumestan isolated from Glycine tabacina, inhibits IL-1β-induced inflammation in SW982 human synovial cells and suppresses RANKL-induced osteoclastogenesis: From network pharmacology to experimental pharmacology Journal article
Journal of Ethnopharmacology, 2020,Volume: 258
Authors:  Tu,Yanbei;  Wang,Kai;  Tan,Lihua;  Han,Bing;  Hu,Yuanjia;  Ding,Hang;  He,Chengwei
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Dolichosin A  Glycine tabacina (Labill.) benth  Inflammation  Network pharmacology  Osteoclastogenesis  Rheumatoid arthritis  
Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation Journal article
Asian Journal of Pharmaceutical Sciences, 2020,Volume: 15,Issue: 4,Page: 518-528
Authors:  Xiong,Sha;  Liu,Wei;  Zhou,Yile;  Mo,Yousheng;  Liu,Yao;  Chen,Xiaojia;  Pan,Huafeng;  Yuan,Dongsheng;  Wang,Qi;  Chen,Tongkai
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Anti-Parkinsonian efficacy  Brain permeability  Nanocrystals  Oral absorption  Resveratrol  
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway Journal article
Journal of Cellular and Molecular Medicine, 2020,Volume: 24,Issue: 11,Page: 6208-6219
Authors:  Yan,Fengxia;  Liao,Rifang;  Silva,Marta;  Li,Shuai;  Jiang,Yizhou;  Peng,Tangming;  Lazarovici,Philip;  Zheng,Wenhua
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cell death  FoxO3a  nuclear accumulation  Pristimerin  uveal melanoma  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:  Zhou,Hefeng;  Li,Shengnan;  Li,Chuwen;  Yang,Xuanjun;  Li,Haitao;  Zhong,Hanbing;  Lu,Jia Hong;  Lee,Simon Ming Yuen
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Degradation  Neuroprotection  Parkinson's disease  Proteasome  α-synuclein  
Dimeric Diarylheptanoids with Neuroprotective Activities from Rhizomes of Alpinia officinarum Journal article
ACS Omega, 2020
Authors:  Liu,Hui;  Wang,Xiaojun;  Shi,Qiaoyun;  Li,Liuren;  Zhang,Qinghua;  Wu,Zhen Long;  Huang,Xiao Jun;  Zhang,Qing Wen;  Ye,Wen Cai;  Wang,Ying;  Shi,Lei
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Phanginin R induces cytoprotective autophagy via JNK/C-JUN signaling pathway in non-small cell lung cancer A549 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2020,Volume: 20,Issue: 8,Page: 982-988
Authors:  Zhang,Le Le;  Bao,Han;  Xu,Yu Lian;  Jiang,Xiao Ming;  Li,Wei;  Zou,Liang;  Lin,Li Gen;  Lu,Jin Jian
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Anti-cancer  Autophagy  C-Jun  JNK  Non-small cell lung cancer  Phanginin R