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Bioactive compounds from marine macroalgae and their hypoglycemic benefits
Zhao, Chao1,2,5; Yang, Chengfeng1; Liu, Bin1; Lin, Luan5; Sarker, Satyajit D.3; Nahar, Lutfun3; Yu, Hua4; Cao, Hui4; Xiao, Jianbo4

Diabetes mellitus is a group of chronic metabolic disorders characterized by hyperglycemia due to defects in insulin action and/or secretion. It is a worldwide problem which has led to illness and premature mortality for many people, and the number of diabetes cases has been rising sharply. Unluckily, many conventional anti diabetic agents either show limited efficacy or serious mechanism-based side effects. Marine macroalgae possess tremendous nutritional value and have been well-known to cure and prevent diabetes. An increased interest in various bioactive natural products from marine macroalgae, as a potential source of effective antidiabetic agents, has been observed in recent years. The effects of macroalgae may delay the development of diabetes and alter the metabolic abnormalities through various mechanisms of actions. This review provides an overview of marine macroalgae used to prevent and manage diabetes and explores the hypoglycemic properties of macroalgae-derived bioactive compounds such as polyphenol, bromophenols, sulfated polysaccharides, fucoidan, fucosterol, phlorotannins, carotenoid pigments and fucoxanthin with their probable mechanisms behind hypoglycemic activity.

KeywordPhaeophyta Rhodophyta Chlorophyta Bioactive Compounds Hypoglycemic Activity
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Indexed BySCIE
WOS Research AreaFood Science & Technology
WOS SubjectFood Science & Technology
WOS IDWOS:000424962100001
The Source to ArticleWOS
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Cited Times [WOS]:72   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China
2.Department of Chemistry, University of California, Davis 95616, USA
3.Medicinal Chemistry and Natural Products Research Group, School of Pharmacy and Biomolecular Sciences, Faculty of Science, Liverpool John Moores University, James Parsons Building, Byrom Street, Liverpool L3 3AF, UK
4.Institute of Chinese Medical Sciences, State Key Laboratory of Quality Control in Chinese Medicine, University of Macau, Macau
5.Fujian Province Key Laboratory for the Development of Bioactive Material from Marine Algae, Quanzhou Normal University, Quanzhou 362000, China
Recommended Citation
GB/T 7714
Zhao, Chao,Yang, Chengfeng,Liu, Bin,et al. Bioactive compounds from marine macroalgae and their hypoglycemic benefits[J]. TRENDS IN FOOD SCIENCE & TECHNOLOGY,2018,72:1-12.
APA Zhao, Chao,Yang, Chengfeng,Liu, Bin,Lin, Luan,Sarker, Satyajit D.,Nahar, Lutfun,Yu, Hua,Cao, Hui,&Xiao, Jianbo.(2018).Bioactive compounds from marine macroalgae and their hypoglycemic benefits.TRENDS IN FOOD SCIENCE & TECHNOLOGY,72,1-12.
MLA Zhao, Chao,et al."Bioactive compounds from marine macroalgae and their hypoglycemic benefits".TRENDS IN FOOD SCIENCE & TECHNOLOGY 72(2018):1-12.
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