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Prescription patterns of psychotropic medications and use of electroconvulsive therapy in Chinese patients with dementia
Li L.7; Wang Z.-M.5; Chiu H.F.K.4; Ungvari G.S.6; Ng C.H.2; Tse A.W.Y.4; Lok G.K.I.; Zhou J.-S.1; Xiang Y.-T.7
2015-09-01
Source PublicationInternational Journal of Clinical Pharmacology and Therapeutics
ISSN09461965
Volume53Issue:9Pages:722-727
Abstract

Background: Little is known about psychiatric pharmacotherapy and somatic treatments in dementia in China. This study examined the prescription patterns of psychotropic medications and use of electroconvulsive therapy (ECT) in dementia patients hospitalized in a psychiatric institution in Beijing, China. Methods: This was a retrospective chart review of 401 patients with dementia treated over a period of 7 years (2007 - 2013) in a university-affiliated psychiatric institution in Beijing. Socio-demographic and clinical data were collected from the electronic chart management system (ECMS) for discharged patients. Results: Nearly all patients (96.8%) received psychotropic medications in order of frequency: second-generation antipsychotics (83.0%), benzodiazepines (77.8%), first generation antipsychotics (39.7%), antidepressants (29.7%), and mood stabilizers (24.7%). The rate of polypharmacy and ECT use was 82.0% and 3.7%, respectively. Prescription of mood stabilizers was associated with longer length of hospitalization. Conclusions: In a major psychiatric hospital in China, ECT was sporadically used in patients with dementia, while the vast majority of patients received at least one type of psychotropic medication. Factors contributing to the high use of psychopharmacological interventions in this population warrant further investigations.

KeywordChina Dementia Electroconvulsive Therapy Psychotropic Medications
DOI10.5414/CP202361
URLView the original
Indexed BySCI
Language英语
WOS Research AreaPharmacology & Pharmacy
WOS SubjectPharmacology & Pharmacy
WOS IDWOS:000362934400003
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Cited Times [WOS]:3   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Central South University China
2.University of Melbourne
3.University of Western Australia
4.Chinese University of Hong Kong
5.Capital Medical University China
6.University of Notre Dame Australia
7.Universidade de Macau
Recommended Citation
GB/T 7714
Li L.,Wang Z.-M.,Chiu H.F.K.,et al. Prescription patterns of psychotropic medications and use of electroconvulsive therapy in Chinese patients with dementia[J]. International Journal of Clinical Pharmacology and Therapeutics,2015,53(9):722-727.
APA Li L..,Wang Z.-M..,Chiu H.F.K..,Ungvari G.S..,Ng C.H..,...&Xiang Y.-T..(2015).Prescription patterns of psychotropic medications and use of electroconvulsive therapy in Chinese patients with dementia.International Journal of Clinical Pharmacology and Therapeutics,53(9),722-727.
MLA Li L.,et al."Prescription patterns of psychotropic medications and use of electroconvulsive therapy in Chinese patients with dementia".International Journal of Clinical Pharmacology and Therapeutics 53.9(2015):722-727.
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