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Listening to light scattering in turbid media: Quantitative optical scattering imaging using photoacoustic measurements with one-wavelength illumination
Yuan Z.2; Li X.1; Xi L.1
2014
Source PublicationJournal of Optics (United Kingdom)
ISSN20408986 20408978
Volume16Issue:6
Abstract

Biomedical photoacoustic tomography (PAT), as a potential imaging modality, can visualize tissue structure and function with high spatial resolution and excellent optical contrast. It is widely recognized that the ability of quantitatively imaging optical absorption and scattering coefficients from photoacoustic measurements is essential before PAT can become a powerful imaging modality. Existing quantitative PAT (qPAT), while successful, has been focused on recovering absorption coefficient only by assuming scattering coefficient a constant. An effective method for photoacoustically recovering optical scattering coefficient is presently not available. Here we propose and experimentally validate such a method for quantitative scattering coefficient imaging using photoacoustic data from one-wavelength illumination. The reconstruction method developed combines conventional PAT with the photon diffusion equation in a novel way to realize the recovery of scattering coefficient. We demonstrate the method using various objects having scattering contrast only or both absorption and scattering contrasts embedded in turbid media. The listening-to-light-scattering method described will be able to provide high resolution scattering imaging for various biomedical applications ranging from breast to brain imaging.

KeywordBiomedical Optics Diffuse Optical Imaging Photoacoustic Imaging
DOI10.1088/2040-8978/16/6/065301
URLView the original
WOS Research AreaOptics
WOS SubjectOptics
WOS IDWOS:000337677200013
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Cited Times [WOS]:12   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.University of Florida
2.Universidade de Macau
Recommended Citation
GB/T 7714
Yuan Z.,Li X.,Xi L.. Listening to light scattering in turbid media: Quantitative optical scattering imaging using photoacoustic measurements with one-wavelength illumination[J]. Journal of Optics (United Kingdom),2014,16(6).
APA Yuan Z.,Li X.,&Xi L..(2014).Listening to light scattering in turbid media: Quantitative optical scattering imaging using photoacoustic measurements with one-wavelength illumination.Journal of Optics (United Kingdom),16(6).
MLA Yuan Z.,et al."Listening to light scattering in turbid media: Quantitative optical scattering imaging using photoacoustic measurements with one-wavelength illumination".Journal of Optics (United Kingdom) 16.6(2014).
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