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Polymer dots with broadband optical absorption (500 nm - 700 nm) and high-efficiency photoacoustic conversion for in vivo multispectral photoacoustic imaging
Zhang J.; Yuan Z.
2016
Conference NameConference on Optics in Health Care and Biomedical Optics VII
Source PublicationProceedings of SPIE - The International Society for Optical Engineering
Volume10024
Conference DateOCT 12-14, 2016
Conference PlaceBeijing, PEOPLES R CHINA
Abstract

Multi-spectral photoacoustic (MSPA) imaging can extract quantitative information of interesting component from morphological photoacoustic image of targets. A probe with an optimal optical absorption can be detected by MSPA imaging with higher sensitivity and specificity. Here we developed a Nano polymers dots (P-dots) for MSPA imaging that has a high photoacoustic conversion efficiency in a broad optical absorbing band (500 nm - 700 nm). In vivo MSPA imaging experiment was successfully performed in mouse model. The relative concentration map of P-dots was exactly obtained from the background of tissues, which demonstrated the potential use of P-dots in the bio-imaging field based on MSPA imaging.

KeywordBroadband Optical Absorption High Photo-acoustic Conversion Efficiency. Multi-spectral Photoacoustic Imaging Polymers Dots
DOI10.1117/12.2245654
URLView the original
Indexed ByCPCI-S
Language英語English
WOS Research AreaOptics ; Radiology, Nuclear Medicine & Medical Imaging
WOS SubjectOptics ; Radiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000392269600038
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Document TypeConference paper
CollectionFaculty of Health Sciences
AffiliationUniversidade de Macau
Recommended Citation
GB/T 7714
Zhang J.,Yuan Z.. Polymer dots with broadband optical absorption (500 nm - 700 nm) and high-efficiency photoacoustic conversion for in vivo multispectral photoacoustic imaging[C],2016.
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