UM
Affiliated with RCfalse
Status已發表Published
HIF-1: structure, biology and natural modulators
Yang, Chao1; Zhong, Zhang Feng2; Wang, Sheng Peng2; Vong, Chi Teng2; Yu, Bin3,4; Wang, Yi Tao2
2021-07-01
Source PublicationChinese journal of natural medicines
ISSN2095-6975
Volume19Issue:7Pages:521-527
Abstract

Hypoxia-inducible factor 1 (HIF-1), as a main transcriptional regulator of metabolic adaptation to changes in the oxygen environment, participates in many physiological and pathological processes in the body, and is closely related to the pathogenesis of many diseases. This review outlines the mechanisms of HIF-1 activation, its signaling pathways, natural inhibitors, and its roles in diseases. This article can provide new insights in the diagnosis and treatment of human diseases, and recent progress on the development of HIF-1 inhibitors.

KeywordHuman Disease Hypoxia Inhibitor Natural Product
DOI10.1016/S1875-5364(21)60051-1
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS SubjectIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS IDWOS:000671867000005
Scopus ID2-s2.0-85111421419
Fulltext Access
Citation statistics
Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorYu, Bin; Wang, Yi Tao
Affiliation1.National Engineering Research Center for Marine Aquaculture, Institute of Innovation and Application, Zhejiang Ocean Uni-versity, Zhoushan 316022, China;
2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, China
3.School of Pharmaceutical Sciences and Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou 450001, China; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China
4.State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Yang, Chao,Zhong, Zhang Feng,Wang, Sheng Peng,et al. HIF-1: structure, biology and natural modulators[J]. Chinese journal of natural medicines,2021,19(7):521-527.
APA Yang, Chao,Zhong, Zhang Feng,Wang, Sheng Peng,Vong, Chi Teng,Yu, Bin,&Wang, Yi Tao.(2021).HIF-1: structure, biology and natural modulators.Chinese journal of natural medicines,19(7),521-527.
MLA Yang, Chao,et al."HIF-1: structure, biology and natural modulators".Chinese journal of natural medicines 19.7(2021):521-527.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Yang, Chao]'s Articles
[Zhong, Zhang Feng]'s Articles
[Wang, Sheng Peng]'s Articles
Baidu academic
Similar articles in Baidu academic
[Yang, Chao]'s Articles
[Zhong, Zhang Feng]'s Articles
[Wang, Sheng Peng]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Yang, Chao]'s Articles
[Zhong, Zhang Feng]'s Articles
[Wang, Sheng Peng]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.