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Left Atrium Wall-mapping Application for Wall Thickness Visualisation
Sun,Jing Yi1; Yun,Chun Ho2,3; Mok,Greta S.P.4; Liu,Yi Hwa5; Hung,Chung Lieh2,6,7; Wu,Tung Hsin1; Alaiti,Mohamad Amer8; Eck,Brendan L.8; Fares,Anas8; Bezerra,Hiram G.8
2018-12-01
Source PublicationScientific Reports
Volume8Issue:1
AbstractThe measurement method for the LA wall thickness (WT) using cardiac computed tomography (CT) is observer dependent and cannot provide a rapid and comprehensive visualisation of the global LA WT. We aim to develop a LA wall-mapping application to display the global LA WT on a coplanar plane. The accuracy, intra-observer, and inter-observer reproducibility of the application were validated using digital/physical phantoms, and CT images of eight patients. This application on CT-based LA WT measures were further validated by testing six pig cardiac specimens. To evaluate its accuracy, the expanded maps of the physical phantom and pig LA were generated from the CT images and compared with the expanded map of the digital phantom and LA wall of pig heart. No significant differences (p > 0.05) were found between physical phantom and digital phantom as well as pig heart specimen and CT images using our application. Moreover, the analysis was based on the LA physical phantom or images of clinical patients; the results consistently demonstrated high intra-observer reproducibility (ICC > 0.9) and inter-observer reproducibility (ICC > 0.8) and showed good correlation between measures of pig heart specimen and CT data (r = 0.96, p < 0.001). The application can process and analyse the LA architecture for further visualisation and quantification.
DOI10.1038/s41598-018-22089-z
URLView the original
Language英语
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Cited Times [WOS]:3   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Department of Biomedical Imaging and Radiological Sciences,National Yang Ming University,Taipei,Taiwan
2.Department of Medicine,Mackay Medical College,Mackay Medicine Nursing and Management College,Taipei,Taiwan
3.Department of Radiology,Mackay Memorial Hospital,Taipei,Taiwan
4.Biomedical Imaging Laboratory,Department of Electrical and Computer Engineering,Faculty of Science and Technology,University of Macau,Macao
5.Department of Internal Medicine (Cardiology),Yale University,New Haven,United States
6.Department of Internal Medicine (Cardiology),Mackay Memorial Hospital,Taipei,Taiwan
7.Institute of Clinical Medicine,Cardiovascular Research Center,Taipei,Taiwan
8.Cardiovascular Department,University Hospitals Case Medical Center,Cleveland,United States
Recommended Citation
GB/T 7714
Sun,Jing Yi,Yun,Chun Ho,Mok,Greta S.P.,et al. Left Atrium Wall-mapping Application for Wall Thickness Visualisation[J]. Scientific Reports,2018,8(1).
APA Sun,Jing Yi,Yun,Chun Ho,Mok,Greta S.P.,Liu,Yi Hwa,Hung,Chung Lieh,Wu,Tung Hsin,Alaiti,Mohamad Amer,Eck,Brendan L.,Fares,Anas,&Bezerra,Hiram G..(2018).Left Atrium Wall-mapping Application for Wall Thickness Visualisation.Scientific Reports,8(1).
MLA Sun,Jing Yi,et al."Left Atrium Wall-mapping Application for Wall Thickness Visualisation".Scientific Reports 8.1(2018).
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