UM
Recent advances in nanomaterial-based synergistic combination cancer immunotherapy
Sang,Wei1,2; Zhang,Zhan1,2; Dai,Yunlu1,2; Chen,Xiaoyuan3
2019-07-21
Source PublicationChemical Society Reviews
ISSN0306-0012
Volume48Issue:14Pages:3771-3810
AbstractIn recent years, conventional treatments including surgery, chemotherapy and radiotherapy have been the main approaches in tumour therapy. Cancer immunotherapy is a new therapeutic modality to fight cancer by harnessing the power of patients' own immune system. Ongoing research related to these therapies has demonstrated their advantages and intrinsic limitations. Nanomaterial-based platforms are utilized in these emerging fields. In particular, a combination of other treatment methods with cancer immunotherapy to achieve precision medicine and prevent recurrence and metastasis, could improve patients' outcome. The combined multiple treatments have superior efficacy to any monotherapy alone in producing improved anti-cancer activity. Therefore, it's necessary to summarise research advances in nanomaterial-based combination cancer immunotherapy contributing to clinical transformation. This review is based on the principles of cancer immunotherapy and the combined treatment design reflected by advances in materials science, including the structures of nanoplatforms and their underlying mechanisms towards cancer. The ultimate goals are to stimulate the design of better strategies for versatile use in the future based on biomaterial engineering methods to enhance the efficacy of combined cancer treatments, and to provide new ideas for the prospects of a synergistic cancer combination immunotherapy for clinical application transformation.
DOI10.1039/c8cs00896e
URLView the original
Language英语
Scopus ID2-s2.0-85068997035
Fulltext Access
Citation statistics
Cited Times [WOS]:102   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorDai,Yunlu
Affiliation1.Cancer Centre,Faculty of Health Sciences,University of Macau,999078,Macao
2.Institute of Translational Medicine,Faculty of Health Sciences,University of Macau,999078,Macao
3.Laboratory of Molecular Imaging and Nanomedicine,National Institute of Biomedical Imaging and Bioengineering,National Institutes of Health,Bethesda,20892,United States
First Author AffilicationCancer Centre;  Faculty of Health Sciences
Corresponding Author AffilicationCancer Centre;  Faculty of Health Sciences
Recommended Citation
GB/T 7714
Sang,Wei,Zhang,Zhan,Dai,Yunlu,et al. Recent advances in nanomaterial-based synergistic combination cancer immunotherapy[J]. Chemical Society Reviews,2019,48(14):3771-3810.
APA Sang,Wei,Zhang,Zhan,Dai,Yunlu,&Chen,Xiaoyuan.(2019).Recent advances in nanomaterial-based synergistic combination cancer immunotherapy.Chemical Society Reviews,48(14),3771-3810.
MLA Sang,Wei,et al."Recent advances in nanomaterial-based synergistic combination cancer immunotherapy".Chemical Society Reviews 48.14(2019):3771-3810.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Sang,Wei]'s Articles
[Zhang,Zhan]'s Articles
[Dai,Yunlu]'s Articles
Baidu academic
Similar articles in Baidu academic
[Sang,Wei]'s Articles
[Zhang,Zhan]'s Articles
[Dai,Yunlu]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Sang,Wei]'s Articles
[Zhang,Zhan]'s Articles
[Dai,Yunlu]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.