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Prescribing patterns of psychotropic medications and clinical features in patients with major depressive disorder with and without comorbid dysthymia in China
Feng,Yuan1,2,3; Sha,Sha1,2,3; Hu,Chen1,2,3; Wang,Gang1,2,3; Ungvari,Gabor S.4,5; Chiu,Helen F.K.6; Ng,Chee H.7; Si,Tian Mei8; Chen,Da Fang9; Fang,Yi Ru10; Lu,Zheng11; Yang,Hai Chen12; Hu,Jian13; Chen,Zhi Yu14; Huang,Yi15; Sun,Jing16; Wang,Xiao Ping17; Li,Hui Chun18; Zhang,Jin Bei19; Xiang,Yu Tao20
2017-03-01
Source PublicationAsia-Pacific Psychiatry
ISSN1758-5864
Volume9Issue:1
AbstractIntroduction: Little has been reported about the demographic and clinical features of major depressive disorder (MDD) with comorbid dysthymia in Chinese patients. This study examined the frequency of comorbid dysthymia in Chinese MDD patients together with the demographic and clinical correlates and prescribing patterns of psychotropic drugs. Methods: Consecutively collected sample of 1178 patients with MDD were examined in 13 major psychiatric hospitals in China. Patients' demographic and clinical characteristics and psychotropic drugs prescriptions were recorded using a standardized protocol and data collection procedure. The diagnosis of dysthymia was established using the Mini International Neuropsychiatric Interview. Medications ascertained included antidepressants, antipsychotics, benzodiazepines, and mood stabilizers. Results: One hundred and three (8.7%) patients fulfilled criteria for dysthymia. In multiple logistic regression analyses, compared to non-dysthymia counterparts, MDD patients with dysthymia had more depressive episodes with atypical features including increased appetite, sleep, and weight gain, more frequent lifetime depressive episodes, and less likelihood of family history of psychiatric disorders. There was no significant difference in the pattern of psychotropic prescription between the 2 groups. Conclusions: There are important differences in the demographic and clinical features of comorbid dysthymia in Chinese MDD patients compared with previous reports. The clinical profile found in this study has implications for treatment decisions.
KeywordChina dysthymia major depressive disorder
DOI10.1111/appy.12261
URLView the original
Language英语
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Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorWang,Gang
Affiliation1.Mood Disorders Center,Beijing Anding Hospital,Capital Medical University,Beijing,China
2.China Clinical Research Center for Mental Disorders,Beijing,China
3.Center of Depression,Beijing Institute for Brain Disorders,Beijing,China
4.The University of Notre Dame Australia / Marian Centre,Perth,Australia
5.School of Psychiatry & Clinical Neurosciences,University of Western Australia,Perth,Australia
6.Department of Psychiatry,Chinese University of Hong Kong,Hong Kong
7.Department of Psychiatry,University of Melbourne,Melbourne,Australia
8.Key Laboratory of Mental Health,Ministry of Mental Health & Peking University Institute of Mental Health,Beijing,China
9.Department of Epidemiology and Biostatistics,Peking University Health Science Center,Beijing,China
10.Division of Mood Disorders,Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai,China
11.Shanghai Tongji Hospital,Tongji University Medical School,Shanghai,China
12.Division of Mood Disorders,Shenzhen Mental Health Centre,Shenzhen,China
13.The First Hospital of Harbin Medical University,Harbin,China
14.Hangzhou Seventh People's Hospital,Hangzhou,China
15.West China Hospital,Sichuan University,Chengdu,China
16.The Affiliated Brain Hospital,Nanjing Medical University,Nanjing,China
17.Mental Health Institute,The Second Xiangya Hospital,Central South University,Changsha,China
18.The Second Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou,China
19.The Third Affiliated Hospital of Sun Yat-Sen University,Guangzhou,China
20.Faculty of Health Sciences,University of Macau,Macao SAR,Macao
Recommended Citation
GB/T 7714
Feng,Yuan,Sha,Sha,Hu,Chen,et al. Prescribing patterns of psychotropic medications and clinical features in patients with major depressive disorder with and without comorbid dysthymia in China[J]. Asia-Pacific Psychiatry,2017,9(1).
APA Feng,Yuan,Sha,Sha,Hu,Chen,Wang,Gang,Ungvari,Gabor S.,Chiu,Helen F.K.,Ng,Chee H.,Si,Tian Mei,Chen,Da Fang,Fang,Yi Ru,Lu,Zheng,Yang,Hai Chen,Hu,Jian,Chen,Zhi Yu,Huang,Yi,Sun,Jing,Wang,Xiao Ping,Li,Hui Chun,Zhang,Jin Bei,&Xiang,Yu Tao.(2017).Prescribing patterns of psychotropic medications and clinical features in patients with major depressive disorder with and without comorbid dysthymia in China.Asia-Pacific Psychiatry,9(1).
MLA Feng,Yuan,et al."Prescribing patterns of psychotropic medications and clinical features in patients with major depressive disorder with and without comorbid dysthymia in China".Asia-Pacific Psychiatry 9.1(2017).
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