The prevalence of depression in menopausal women in China: A meta-analysis of observational studies
Zeng,Liang Nan1,2; Yang,Yuan1,3; Feng,Yuan4; Cui,Xiling5; Wang,Rixin1; Hall,Brian J.6,7; Ungvari,Gabor S.8,9; Chen,Ligang2; Xiang,Yu Tao1
Source PublicationJournal of Affective Disorders
AbstractObjective: Depressive symptoms (depression thereafter) are common among menopausal women but findings across studies have been inconsistent. This meta-analysis examined the pooled prevalence of depression among Chinese menopausal women. Methods: Two investigators independently searched both international (PubMed, EMBASE and PsycINFO) and Chinese (CNKI, WanFang, SinoMed and VIP) databases from their inception date until 9 April 2019. Studies that reported the prevalence of depression as measured by the Hamilton Depression Scale (HAMD) were pooled using a random-effects model. Results: Twenty-three cross-sectional studies were included in the meta-analysis. The pooled prevalence of depression in menopausal Chinese women was 36.3% (95% CI: 27.5–45.1%), with mild depression of 18.6% (95% CI: 13.4–23.8%), moderate depression of 15.3% (95% CI: 9.4–21.3%), and severe depression of 3.7% (95% CI: 1.9–5.5%). Meta-regression analyses revealed that older age (B = 0.12, z = 8.18, p < 0.001) and better study quality (B = 0. 24, z = 8.33, p < 0.001) was significantly associated with higher depression prevalence. Conclusions: Depression is common among menopausal Chinese women. Due to its negative impact on health, regular screening and effective treatments should be developed for this population.
KeywordChina Depression Menopause Meta-analysis
URLView the original
Scopus ID2-s2.0-85067678428
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Cited Times [WOS]:15   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorChen,Ligang
Affiliation1.Unit of Psychiatry,Institute of Translational Medicine,Faculty of Health Sciences,University of Macau,Macao SAR,3/F, Building E12,China
2.Department of Neurosurgery,The Affiliated Hospital of Southwest Medical University,China
3.Department of Psychiatry and Psychology,Southern Medical University Nanfang Hospital,Guangdong,China
4.The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders Beijing Anding Hospital & the Advanced Innovation Center for Human Brain Protection,Capital Medical University,School of Mental Health,Beijing,China
5.Department of Business Administration,Hong Kong Shue Yan University,Hong Kong
6.Global and Community Mental Health Research Group,Department of Psychology,University of Macau,Macao SAR,China
7.Health,Behavior,and Society,Johns Hopkins Bloomberg School of Public Health,Baltimore,United States
8.Division of Psychiatry,School of Medicine,University of Western Australia,Perth,Australia
9.The University of Notre Dame Australia,Fremantle,Australia
First Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Zeng,Liang Nan,Yang,Yuan,Feng,Yuan,et al. The prevalence of depression in menopausal women in China: A meta-analysis of observational studies[J]. Journal of Affective Disorders,2019,256:337-343.
APA Zeng,Liang Nan,Yang,Yuan,Feng,Yuan,Cui,Xiling,Wang,Rixin,Hall,Brian J.,Ungvari,Gabor S.,Chen,Ligang,&Xiang,Yu Tao.(2019).The prevalence of depression in menopausal women in China: A meta-analysis of observational studies.Journal of Affective Disorders,256,337-343.
MLA Zeng,Liang Nan,et al."The prevalence of depression in menopausal women in China: A meta-analysis of observational studies".Journal of Affective Disorders 256(2019):337-343.
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