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Developments in cell culture systems for human pluripotent stem cells
Liu,Weiwei1,2,3; Deng,Chunhao1,2; Godoy-Parejo,Carlos1,2; Zhang,Yumeng1,2; Chen,Guokai1,2
2019-11-01
Source PublicationWorld Journal of Stem Cells
ISSN1948-0210
Volume11Issue:11Pages:968-981
Abstract

Human pluripotent stem cells (hPSCs) are important resources for cell-based therapies and pharmaceutical applications. In order to realize the potential of hPSCs, it is critical to develop suitable technologies required for specific applications. Most hPSC technologies depend on cell culture, and are critically influenced by culture medium composition, extracellular matrices, handling methods, and culture platforms. This review summarizes the major technological advances in hPSC culture, and highlights the opportunities and challenges in future therapeutic applications.

KeywordCell Culture Culture Medium Embryoid Bodies Human Embryonic Stem Cells Human Pluripotent Stem Cells Signal Transduction Stem Cell Niche
DOI10.4252/wjsc.v11.i11.968
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaCell Biology
WOS SubjectCell & Tissue Engineering ; Cell Biology
WOS IDWOS:000512754600005
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Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorChen,Guokai
Affiliation1.Centre of Reproduction,Development and Aging,Faculty of Health Sciences,University of Macau,Macau,999078,China
2.Institute of Translational Medicine,Faculty of Health Sciences,University of Macau,Macau,999078,China
3.Bioimaging and Stem Cell Core Facility,Faculty of Health Sciences,University of Macau,Macau,999078,China
First Author AffilicationFaculty of Health Sciences
Corresponding Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Liu,Weiwei,Deng,Chunhao,Godoy-Parejo,Carlos,et al. Developments in cell culture systems for human pluripotent stem cells[J]. World Journal of Stem Cells,2019,11(11):968-981.
APA Liu,Weiwei,Deng,Chunhao,Godoy-Parejo,Carlos,Zhang,Yumeng,&Chen,Guokai.(2019).Developments in cell culture systems for human pluripotent stem cells.World Journal of Stem Cells,11(11),968-981.
MLA Liu,Weiwei,et al."Developments in cell culture systems for human pluripotent stem cells".World Journal of Stem Cells 11.11(2019):968-981.
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