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Two-dimensional MXene-based materials for photothermal therapy
Huang,Zhongming1; Cui,Xiao1; Li,Shengliang1; Wei,Jinchao2,3; Li,Peng2; Wang,Yitao2; Lee,Chun Sing1
Source PublicationNanophotonics

MXenes, a new family of two-dimensional materials, are also known as transition metal carbides and nitride, with a general formula of Mn+1XnTx (n = 1-3). Their inherent metallic conductivity and hydrophilic nature endow MXenes with fascinating physicochemical properties (optical, electronic, magnetic, light-to-heat conversion. etc.). The ultrathin layer structure and photothermal property attract many interests in biomedical applications, especially as phototherapeutic agents for cancer treatment. In this review, we summarize the recent progress of MXenes in the field of photothermal therapy and highlight the crucial biotic index for their preparation and evaluation. First, we introduce the main strategies for the preparation and surface modifications of biologically applied MXenes. Then, representative cases in the field of MXene-based photothermal application, such as photothermal therapy, synergistic therapy, and targeting treatments, are reviewed. Finally, the cytotoxicity and in vivo long-term biosafety are introduced. We also propose the underlying challenges and perspectives for MXene applications in terms of photothermal therapy.

KeywordMxenes Photothermal Therapy Synergistic Therapy Two-dimensional Materials
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Indexed BySCIE
WOS Research AreaScience & Technology - Other Topics ; Materials Science ; Optic ; Physics
WOS SubjectNanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Optics ; Physics, Applied
WOS IDWOS:000549189300007
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Cited Times [WOS]:5   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorLi,Shengliang
Affiliation1.Center of Super-Diamond and Advanced Films (COSDAF),Department of Chemistry,City University of Hong Kong,Hong Kong,999077,Hong Kong
2.Institute of Chinese Medical Sciences,State Key Laboratory of Quality Research in Chinese Medicine,University of Macau,Macao
3.Institute of Traditional Chinese Medicine and Natural Products,Coll. of Pharm./Guangdong Prov. Key Lab. of Pharmacodynamic Constituents of Tcm and New Drugs Res.,Jinan University,Guangzhou,China
Recommended Citation
GB/T 7714
Huang,Zhongming,Cui,Xiao,Li,Shengliang,et al. Two-dimensional MXene-based materials for photothermal therapy[J]. Nanophotonics,2020,9(8):2233-2249.
APA Huang,Zhongming,Cui,Xiao,Li,Shengliang,Wei,Jinchao,Li,Peng,Wang,Yitao,&Lee,Chun Sing.(2020).Two-dimensional MXene-based materials for photothermal therapy.Nanophotonics,9(8),2233-2249.
MLA Huang,Zhongming,et al."Two-dimensional MXene-based materials for photothermal therapy".Nanophotonics 9.8(2020):2233-2249.
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