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Research and development of anti-Parkinson’s drugs: an analysis from the perspective of technology flows measured by patent citations
Qu,Jingwen; Lu,Jiahong; Hu,Yuanjia
2019-02-01
Source PublicationExpert Opinion on Therapeutic Patents
ISSN1354-3776
Volume29Issue:2Pages:127-135
AbstractIntroduction: By 2020, nearly one million people will live with Parkinson’s disease (PD) in the U.S. This disorder has a significant impact on patients’ quality of life and is a burden on families and society. Protracted efforts have been made to treat the disease. Cumulative technological innovations are encapsulated by patents, and patent citations have been used to analyze technology diffusion processes in R&D, which is essential to identifying technology evolution trends and providing a review of PD treatment from the perspective of technology flows. Areas covered: A patent citation network was utilized to analyze technology flows. Patents related to anti-PD drugs were collected from the U.S. Patent and Trademark Office (U.S. PTO) database. A total of 1,231 patents and 2,995 internal citations granted between 1988 and 2017 were included and analyzed. Expert opinion: To launch drugs with greater efficiency and safety, approaches such as long-acting sustained release, controlled osmotic release, and other novel drug delivery systems should be emphasized. Multi-target agents could effectively reduce side effects in mono-drug therapy and are worth further exploration. Investors should keep an eye on alpha-synuclein–related therapy, gene therapy, and other experimental therapies that might trigger a historic revolution in the treatment domain.
KeywordParkinson’s disease patent citation network research and development technology evolution technology flow
DOI10.1080/13543776.2019.1567712
URLView the original
Language英语
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Cited Times [WOS]:4   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorHu,Yuanjia
AffiliationState Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,University of Macau,Taipa,China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Qu,Jingwen,Lu,Jiahong,Hu,Yuanjia. Research and development of anti-Parkinson’s drugs: an analysis from the perspective of technology flows measured by patent citations[J]. Expert Opinion on Therapeutic Patents,2019,29(2):127-135.
APA Qu,Jingwen,Lu,Jiahong,&Hu,Yuanjia.(2019).Research and development of anti-Parkinson’s drugs: an analysis from the perspective of technology flows measured by patent citations.Expert Opinion on Therapeutic Patents,29(2),127-135.
MLA Qu,Jingwen,et al."Research and development of anti-Parkinson’s drugs: an analysis from the perspective of technology flows measured by patent citations".Expert Opinion on Therapeutic Patents 29.2(2019):127-135.
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