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A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks
Fang,Evandro F.1,2,3,4,5; Xie,Chenglong1,6; Schenkel,Joseph A.7; Wu,Chenkai8,9; Long,Qian8; Cui,Honghua10,11; Aman,Yahyah1; Frank,Johannes1; Liao,Jing12,13; Zou,Huachun14,15; Wang,Ninie Y.16; Wu,Jing17; Liu,Xiaoting18; Li,Tao19,20; Fang,Yuan21; Niu,Zhangming22; Yang,Guang23; Hong,Jiangshui24; Wang,Qian5; Chen,Guobing4; Li,Jun25; Chen,Hou Zao25; Kang,Lin26; Su,Huanxing27; Gilmour,Brian C.2; Zhu,Xinqiang28,29; Jiang,Hong30,31,32; He,Na33,34,35; Tao,Jun3; Leng,Sean Xiao36; Tong,Tanjun37; Woo,Jean38
2020-12-01
Source PublicationAgeing Research Reviews
ISSN1568-1637
Volume64
Abstract

One of the key issues facing public healthcare is the global trend of an increasingly ageing society which continues to present policy makers and caregivers with formidable healthcare and socio-economic challenges. Ageing is the primary contributor to a broad spectrum of chronic disorders all associated with a lower quality of life in the elderly. In 2019, the Chinese population constituted 18 % of the world population, with 164.5 million Chinese citizens aged 65 and above (65+), and 26 million aged 80 or above (80+). China has become an ageing society, and as it continues to age it will continue to exacerbate the burden borne by current family and public healthcare systems. Major healthcare challenges involved with caring for the elderly in China include the management of chronic non-communicable diseases (CNCDs), physical frailty, neurodegenerative diseases, cardiovascular diseases, with emerging challenges such as providing sufficient dental care, combating the rising prevalence of sexually transmitted diseases among nursing home communities, providing support for increased incidences of immune diseases, and the growing necessity to provide palliative care for the elderly. At the governmental level, it is necessary to make long-term strategic plans to respond to the pressures of an ageing society, especially to establish a nationwide, affordable, annual health check system to facilitate early diagnosis and provide access to affordable treatments. China has begun work on several activities to address these issues including the recent completion of the of the Ten-year Health-Care Reform project, the implementation of the Healthy China 2030 Action Plan, and the opening of the National Clinical Research Center for Geriatric Disorders. There are also societal challenges, namely the shift from an extended family system in which the younger provide home care for their elderly family members, to the current trend in which young people are increasingly migrating towards major cities for work, increasing reliance on nursing homes to compensate, especially following the outcomes of the ‘one child policy’ and the ‘empty-nest elderly’ phenomenon. At the individual level, it is important to provide avenues for people to seek and improve their own knowledge of health and disease, to encourage them to seek medical check-ups to prevent/manage illness, and to find ways to promote modifiable health-related behaviors (social activity, exercise, healthy diets, reasonable diet supplements) to enable healthier, happier, longer, and more productive lives in the elderly. Finally, at the technological or treatment level, there is a focus on modern technologies to counteract the negative effects of ageing. Researchers are striving to produce drugs that can mimic the effects of ‘exercising more, eating less’, while other anti-ageing molecules from molecular gerontologists could help to improve ‘healthspan’ in the elderly. Machine learning, ‘Big Data’, and other novel technologies can also be used to monitor disease patterns at the population level and may be used to inform policy design in the future. Collectively, synergies across disciplines on policies, geriatric care, drug development, personal awareness, the use of big data, machine learning and personalized medicine will transform China into a country that enables the most for its elderly, maximizing and celebrating their longevity in the coming decades. 

KeywordAgeing Policy Dementia Inflammageing Oral Ageing Sexually Transmitted Diseases Square Dancing
DOI10.1016/j.arr.2020.101174
URLView the original
Indexed BySCIE ; SSCI
Language英語English
WOS Research AreaCell Biology ; Geriatrics & Gerontology
WOS SubjectCell Biology ; Geriatrics & Gerontology
WOS IDWOS:000595935300013
Scopus ID2-s2.0-85091870837
Fulltext Access
Citation statistics
Cited Times [WOS]:14   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorFang,Evandro F.
Affiliation1.Department of Clinical Molecular Biology,University of Oslo and Akershus University Hospital,Lørenskog,1478,Norway
2.The Norwegian Centre on Healthy Ageing (NO-Age),Oslo,Norway
3.Department of Hypertension and Vascular Disease,The First Affiliated Hospital,Sun Yat-Sen University,Guangzhou,510080,China
4.Institute of Geriatric Immunology,School of Medicine,Jinan University,Guangzhou,510632,China
5.Department of Geriatrics,The First Affiliated Hospital,Zhengzhou University,Zhengzhou,450052,China
6.Department of Neurology,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China
7.Durham University Department of Sports and Exercise Sciences,Durham,United Kingdom
8.Global Health Research Center,Duke Kunshan University,Kunshan,215316,China
9.Duke Global Health Institute,Duke University,Durham,27710,United States
10.Department of Endodontics,Shanghai Stomatological Hospital,Fudan University,China
11.Oral Biomedical Engineering Laboratory,Shanghai Stomatological Hospital,Fudan University,China
12.Department of Medical Statistics and Epidemiology,School of Public Health,Sun Yat-sen University,Guangzhou,510275,China
13.Sun Yat-sen Global Health Institute,Institute of State Governance,Sun Yat-sen University,Guangzhou,510275,China
14.School of Public Health (Shenzhen),Sun Yat-sen University,Shenzhen,China
15.Kirby Institute,University of New South Wales,Sydney,Australia
16.Pinetree Care Group,Beijing,515 Tower A, Guomen Plaza, Chaoyang District,100028,China
17.Department of Sociology and Work Science,University of Gothenburg,Gothenburg,SE-405 30,Sweden
18.School of Public Affairs,Zhejiang University,Hangzhou,310058,China
19.BGI-Shenzhen,Beishan Industrial Zone,Shenzhen,518083,China
20.China National GeneBank,BGI-Shenzhen,Shenzhen,518120,China
21.Department of Public Health,Erasmus University Medical Centre,Rotterdam,Netherlands
22.Aladdin Healthcare Technologies Ltd.,London,25 City Rd, Shoreditch,EC1Y 1AA,United Kingdom
23.Cardiovascular Research Centre,Royal Brompton Hospital,London,SW3 6NP,UK; and National Heart and Lung Institute,Imperial College London,London,SW7 2AZ,United Kingdom
24.Mindrank AI,Hangzhou,China
25.Department of Biochemistry and Molecular Biology,The Institute of Basic Medical Sciences,The Chinese Academy of Medical Sciences (CAMS)& Peking Union Medical University (PUMC),Beijing,5 Dondan Santiao Road,100730,China
26.Department of Geriatrics,Peking Union Medical College Hospital,Beijing,100730,China
27.State Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,University of Macau,Macao
28.Department of Toxicology,Zhejiang University School of Public Health,Hangzhou,310058,China
29.The Fourth Affiliated Hospital,Zhejiang University School of Medicine,Yiwu,322000,China
30.Department of Neurology,Xiangya Hospital,Central South University,Changsha,410008,China
31.Key Laboratory of Hunan Province in Neurodegenerative Disorders,Central South University,Changsha,China
32.National Clinical Research Center for Geriatric Disorders,Xiangya Hospital,Central South University,Changsha,410008,China
33.School of Public Health,Fudan University,Shanghai,200032,China
34.Key Laboratory of Public Health Safety of Ministry of Education,Fudan University,Shanghai,200032,China
35.Key Laboratory of Health Technology Assessment of Ministry of Health,Fudan University,Shanghai,200032,China
36.Division of Geriatric Medicine and Gerontology,Johns Hopkins University School of Medicine,Baltimore,5505 Hopkins Bayview Circle,MD 21224,United States
37.Research Center on Ageing,Department of Biochemistry and Molecular Biology,School of Basic Medical Sciences,Peking University Health Science Center,Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function,Beijing,China
38.Department of Medicine and Therapeutics,The Chinese University of Hong Kong,Hong Kong SAR,Hong Kong
Recommended Citation
GB/T 7714
Fang,Evandro F.,Xie,Chenglong,Schenkel,Joseph A.,et al. A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks[J]. Ageing Research Reviews,2020,64.
APA Fang,Evandro F..,Xie,Chenglong.,Schenkel,Joseph A..,Wu,Chenkai.,Long,Qian.,Cui,Honghua.,Aman,Yahyah.,Frank,Johannes.,Liao,Jing.,Zou,Huachun.,Wang,Ninie Y..,Wu,Jing.,Liu,Xiaoting.,Li,Tao.,Fang,Yuan.,Niu,Zhangming.,Yang,Guang.,Hong,Jiangshui.,Wang,Qian.,...&Woo,Jean.(2020).A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks.Ageing Research Reviews,64.
MLA Fang,Evandro F.,et al."A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks".Ageing Research Reviews 64(2020).
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