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Polymer Dots with Broadband Optical Absorption (500 nm-700 nm) and High Efficiency Photoacoustic Conversion for In Vivo Multi-Spectral Photoacoustic Imaging
Jian Zhang; Zhen Yuan
2017
Conference NameConference on Optics in Health Care and Biomedical Optics VII
Source PublicationOPTICS IN HEALTH CARE AND BIOMEDICAL OPTICS VII
Volume0024
Conference DateOCT 12-14, 2016
Conference PlaceBeijing, PEOPLES R CHINA
Publication Place1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
PublisherSPIE-INT SOC OPTICAL ENGINEERING
Abstract

Multi-spectral photoacoustic (MSPA) imaging can extract quantitative information of interesting component from morphological photoacoustic image of targets. A probe with an optimal optical absorption can be detected by MSPA imaging with higher sensitivity and specificity. Here we developed a Nano polymers dots (P-dots) for MSPA imaging that has a high photoacoustic conversion efficiency in a broad optical absorbing band (500 nm - 700 nm). In vivo MSPA imaging experiment was successfully performed in mouse model. The relative concentration map of P-dots was exactly obtained from the background of tissues, which demonstrated the potential use of P-dots in the bio-imaging field based on MSPA imaging.

KeywordMulti-spectral Photoacoustic Imaging Polymers Dots Broadband Optical Absorption High Photo-acoustic Conversion Efficiency
DOI10.1117/12.2245654
URLView the original
Indexed ByCPCI
Language英语
WOS Research AreaOptics ; Radiology, Nuclear Medicine & Medical Imaging
WOS SubjectOptics ; Radiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000392269600038
The Source to ArticleWOS
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Document TypeConference paper
CollectionFaculty of Health Sciences
INSTITUTE OF COLLABORATIVE INNOVATION
AffiliationUniversity of Macau, Bioimaging Core, Faculty of Health Sciences, Macau SAR, China
First Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Jian Zhang,Zhen Yuan. Polymer Dots with Broadband Optical Absorption (500 nm-700 nm) and High Efficiency Photoacoustic Conversion for In Vivo Multi-Spectral Photoacoustic Imaging[C]. 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA:SPIE-INT SOC OPTICAL ENGINEERING,2017.
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