UM  > Institute of Chinese Medical Sciences
In vitro anti-platelet aggregation effects of fourteen fruits and vegetables
Cen Chen1; Qian Zhang1; Feng-Qin Wang1; Chun-Hong Li1; Yuan-Jia Hu2; Zhi-Ning Xia1; Feng-Qing Yang1
2019-01
Source PublicationPAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
ISSN1011-601X
Volume32Issue:1Pages:185-195
Abstract

In the present study, the anti-platelet aggregation activity of 14 vegetables and fruits was tested in vitro. The aqueous, 90% ethanol and ethyl acetate extracts, as well as concentrated juices of 14 foods (fruits and vegetables) were prepared, and the anti-platelet aggregation activity of those extracts was analyzed on a platelet aggregation analyzer in vitro with adenosine 5’-diphosphate (ADP), bovine thrombin (THR) and arachidonic acid (AA) as aggregation inducers, respectively. Aspirin (ASP) was used as the positive control. A number of the tested foods had inhibitory effects in concentration-dependent manner on platelet aggregations induced by various agonists. Especially, some foods such as lemon, leek, garlic, scallion, ginger, tomato and grapefruit showed good anti-platelet aggregation effect similar or higher than that of positive control group i.e. aspirin (ASP). The results of present study provide scientific reference for reasonable selection of daily dietary with supplementary curative effects or prevention of cardiovascular diseases (CVD).

KeywordAnti-platelet Aggregation Adenosine 5'-diphosphate Bovine Thrombin Arachidonic Acid Food Materials
Language英语
WOS Research AreaPharmacology & Pharmacy
WOS SubjectPharmacology & Pharmacy
WOS IDWOS:000460846900026
Fulltext Access
Citation statistics
Cited Times [WOS]:4   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorFeng-Qing Yang
Affiliation1.School of Chemistry and Chemical Engineering, Chongqing University, Chongqing, China
2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, PR China
Recommended Citation
GB/T 7714
Cen Chen,Qian Zhang,Feng-Qin Wang,et al. In vitro anti-platelet aggregation effects of fourteen fruits and vegetables[J]. PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES,2019,32(1):185-195.
APA Cen Chen.,Qian Zhang.,Feng-Qin Wang.,Chun-Hong Li.,Yuan-Jia Hu.,...&Feng-Qing Yang.(2019).In vitro anti-platelet aggregation effects of fourteen fruits and vegetables.PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES,32(1),185-195.
MLA Cen Chen,et al."In vitro anti-platelet aggregation effects of fourteen fruits and vegetables".PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES 32.1(2019):185-195.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Cen Chen]'s Articles
[Qian Zhang]'s Articles
[Feng-Qin Wang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Cen Chen]'s Articles
[Qian Zhang]'s Articles
[Feng-Qin Wang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Cen Chen]'s Articles
[Qian Zhang]'s Articles
[Feng-Qin Wang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.