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Stimuli-responsive nanocarriers constructed from pillar[n]arene-based supra-amphiphiles
Tangxin Xiao1; Lijie Qi1; Weiwei Zhong1; Chen Lin2; Ruibing Wang3; Leyong Wang1,2

Supra-amphiphiles assembled by macrocycle-based host–guest interactions have received considerableattention in recent years due to their dynamic properties and wide applications. Pillar[n]arenes are aunique family of macrocycles which exhibit outstanding host–guest behavior. Developing water-solublepillar[n]arene (WP[n]) based supra-amphiphiles is an effective way to introduce this special macrocycleinto  functional  nanomaterials  through  controlled  self-assembly.  Specifically,  WP[n]-based  supra-amphiphiles can further form different nanomaterials, such as micelles, vesicles, and other types ofnanoparticles (NPs), which may become good candidates for nanocarriers of payloads. Herein, wehighlight recent significant achievements in functional nanocarriers fabricated from supra-amphiphilesbased on WP[n]s. By showing a series of examples, the preparation strategies, characterization, andstimuli-responsive behaviors of these nano-sized assemblies based on WP[n] derivatives are described.Furthermore, some important applications of WP[n]-based nanocarriers, such as drug/gene/proteindelivery, photodynamic/photothermal therapy, and optical materials, are discussed in detail. Finally,future challenges and research directions in this rapidly evolving field are outlined.

Indexed BySCIE
WOS Research AreaChemistry ; Materials Science
WOS SubjectChemistry, Multidisciplinary ; Materials Science, Multidisciplinary
WOS IDWOS:000487811300003
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Cited Times [WOS]:53   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorTangxin Xiao; Chen Lin; Ruibing Wang
Affiliation1.School of Petrochemical Engineering, Advanced Catalysis and GreenManufacturing Collaborative Innovation Center, Changzhou University,Changzhou, 213164, China
2.Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry andChemical Engineering, Nanjing University, Nanjing, 210023, China
3.State Key Laboratory of Quality Research in Chinese Medicine, Institute of ChineseMedical Sciences, University of Macau, Taipa, Macau SAR 999078, China
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Tangxin Xiao,Lijie Qi,Weiwei Zhong,et al. Stimuli-responsive nanocarriers constructed from pillar[n]arene-based supra-amphiphiles[J]. MATERIALS CHEMISTRY FRONTIERS,2019,3(10):1973-1993.
APA Tangxin Xiao,Lijie Qi,Weiwei Zhong,Chen Lin,Ruibing Wang,&Leyong Wang.(2019).Stimuli-responsive nanocarriers constructed from pillar[n]arene-based supra-amphiphiles.MATERIALS CHEMISTRY FRONTIERS,3(10),1973-1993.
MLA Tangxin Xiao,et al."Stimuli-responsive nanocarriers constructed from pillar[n]arene-based supra-amphiphiles".MATERIALS CHEMISTRY FRONTIERS 3.10(2019):1973-1993.
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