UM
A valve-free 2D concentration gradient generator
Tian, Jingxuan; Gao, Yibo; Zhou, Bingpu; Cao, Wenbin; Wu, Xiaoxiao; Wen, Weijia
2017
Source PublicationRSC ADVANCES
ISSN2046-2069
Volume7Issue:45Pages:27833-27839
AbstractWe report a concentration gradient generator featuring valve-free and simultaneous two-dimensional (2D) concentration generation. Each analyte is first diluted by a 1D gradient generator to five different concentrations and then directed into different chambers to generate combinations of different concentrations. The chip consists of three layers, which realizes a 3D fluid path, forming a skywalk structure that allows two perpendicular channels to cross each other in different layers. In this way, this chip could get rid of the pneumatic actuated valves (PAVs) or complicated channel designs that are conventionally adopted in controlling the infusion of multi-analytes. We believe that this design, which makes the chip independent of cumbersome external apparatus in controlling multi-analytes infusion, may potentially benefit the process of making microfluidic chips a portable and cost-effective product.
DOI10.1039/c7ra02139a
URLView the original
Indexed BySCIE
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000402999300001
PublisherROYAL SOC CHEMISTRY
The Source to ArticleWOS
Fulltext Access
Citation statistics
Cited Times [WOS]:3   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Recommended Citation
GB/T 7714
Tian, Jingxuan,Gao, Yibo,Zhou, Bingpu,et al. A valve-free 2D concentration gradient generator[J]. RSC ADVANCES,2017,7(45):27833-27839.
APA Tian, Jingxuan,Gao, Yibo,Zhou, Bingpu,Cao, Wenbin,Wu, Xiaoxiao,&Wen, Weijia.(2017).A valve-free 2D concentration gradient generator.RSC ADVANCES,7(45),27833-27839.
MLA Tian, Jingxuan,et al."A valve-free 2D concentration gradient generator".RSC ADVANCES 7.45(2017):27833-27839.
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