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Development of a multi-band photoacoustic tomography imaging system based on a capacitive micromachined ultrasonic transducer array
Zhang, Jian1,2; Pun, Sio Hang2; Yu, Yuanyu2; Gao, Duyang2; Wang, Jiujiang2; Mak, Peng Un2; Lei, Kin Fong3; Cheng, Ching-Hsiang4; Yuan, Zhen2
2017-05
Source PublicationAPPLIED OPTICS
ISSN1559-128X
Volume56Issue:14Pages:4012-4018
Abstract

Photoacoustic tomography (PAT) as a hybrid technology combines the high optical contrast and high acoustic resolution in a single imaging modality. However, most of the available PAT systems cannot comprehensively or accurately characterize biological systems at multiple length scales due to the use of narrow bandwidth commercial ultrasonic transducers. In this study, we fabricated a novel multi-band capacitive micromachined ultrasonic transducer (CMUT) array, and first developed a CMUT-based multi-band photoacoustic tomography (MBPAT) imaging system. The MBPAT imaging system was examined by the phantom experiment, and then was successfully applied to image the zebrafish in vivo. The imaging results indicated that CMUT-array-based MBPAT can provide a more comprehensive and accurate characterization of biological tissues, which exhibit the potential of MBPAT/CMUT in various areas of biomedical imaging. (C) 2017 Optical Society of America

DOI10.1364/AO.56.004012
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaOptics
WOS IDWOS:000401020800008
PublisherOPTICAL SOC AMER
The Source to ArticleWOS
Fulltext Access
Citation statistics
Cited Times [WOS]:9   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Guangzhou Med Univ, Sch Basic Med Sci, Dept Biomed Engn
2.University of Macau
3.Chang Gung University
4.The Hong Kong Polytechnic University
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Zhang, Jian,Pun, Sio Hang,Yu, Yuanyu,et al. Development of a multi-band photoacoustic tomography imaging system based on a capacitive micromachined ultrasonic transducer array[J]. APPLIED OPTICS,2017,56(14):4012-4018.
APA Zhang, Jian,Pun, Sio Hang,Yu, Yuanyu,Gao, Duyang,Wang, Jiujiang,Mak, Peng Un,Lei, Kin Fong,Cheng, Ching-Hsiang,&Yuan, Zhen.(2017).Development of a multi-band photoacoustic tomography imaging system based on a capacitive micromachined ultrasonic transducer array.APPLIED OPTICS,56(14),4012-4018.
MLA Zhang, Jian,et al."Development of a multi-band photoacoustic tomography imaging system based on a capacitive micromachined ultrasonic transducer array".APPLIED OPTICS 56.14(2017):4012-4018.
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