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Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
作者:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/22
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
Myricanol rescues dexamethasone-induced muscle dysfunction via a sirtuin 1-dependent mechanism Journal article
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2019,Volume: 10,Issue: 2,Page: 429-444
作者:  Shen, SN;  Liao, QW;  Liu, JX;  Pan, RL;  Lee, SMY;  Lin, LG
收藏  |  浏览/下载:82/0  |  提交时间:2020/01/16
Autophagy  Myricanol  Sirt1  Dexamethasone  Muscle Atrophy  Pgc-1 Alpha  
HAMdb: a database of human autophagy modulators with specific pathway and disease information Journal article
JOURNAL OF CHEMINFORMATICS, 2018,Volume: 10
作者:  Wang, Ning-Ning;  Dong, Jie;  Zhang, Lin;  Ouyang, Defang;  Cheng, Yan;  Chen, Alex F.;  Lu, Ai-Ping;  Cao, Dong-Sheng
收藏  |  浏览/下载:10/0  |  提交时间:2018/10/30
Autophagy  Autophagy modulator  Database  Disease  Pathophysiological  Pathway  
Selective autophagy: The new player in the fight against neurodegenerative diseases? Journal article
BRAIN RESEARCH BULLETIN, 2018,Volume: 137,Page: 79-90
作者:  Wu, Ming-Yue;  Song, Ju-Xian;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Li, Min;  Lu, Jia-Hong
收藏  |  浏览/下载:10/0  |  提交时间:2018/10/30
Selective autophagy  Neurodegenerative diesease  Aggrephagy  Chaperone-mediated autophagy  Mitophagy  
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
作者:  Tang, Fan;  Zhou, Xinhua;  Wang, Liang;  Shan, Luchen;  Li, Chuwen;  Zhou, Hefeng;  Lee, Simon Ming-Yuen;  Hoi, Maggie Pui-Man
收藏  |  浏览/下载:12/0  |  提交时间:2018/10/30
Cardioprotection  Anti-oxidative stress  Anti-apoptosis  Autophagy regulation  Zebrafish cardiotoxicity  H9c2 cardiomyocytes  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
CANCER LETTERS, 2018,Volume: 412,Page: 1-9
作者:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong;  Chen, Xiuping;  Zhu, Hong;  Lu, Jin-Jian
收藏  |  浏览/下载:14/0  |  提交时间:2018/10/30
Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Roflupram, a Phosphodiesterase 4 Inhibitior, Suppresses Inflammasome Activation through Autophagy in Microglial Cells Journal article
ACS CHEMICAL NEUROSCIENCE, 2017,Volume: 8,Issue: 11,Page: 2381-2392
作者:  You, Tingting;  Cheng, Yufang;  Zhong, Jiahong;  Bi, Bingtian;  Zeng, Bingqing;  Zheng, Wenhua;  Wang, Haitao;  Xu, Jiangping
收藏  |  浏览/下载:10/0  |  提交时间:2018/10/30
Phosphodiesterase 4  roflupram  autophagy  inflammasome  microglia  neuroinflammation  
Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 44,Page: 77673-77684
作者:  Wu, Ming-Yue;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Tan, Jie-Qiong;  Li, Min;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Wang, Yi-Tao;  Zheng, Wei;  Lu, Jia-Hong
收藏  |  浏览/下载:16/0  |  提交时间:2018/10/30
Dauricine  Daurisoline  Autophagy Blocker  Cancer Cells  Cell Toxicity  
Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells Journal article
REDOX BIOLOGY, 2017,Volume: 12,Page: 367-376
作者:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Wang, Zhao-Yu;  Lu, Jia-Hong;  Liu, Bo;  Chen, Xiuping;  Lu, Jin-Jian
收藏  |  浏览/下载:12/0  |  提交时间:2018/10/30
Chelerythrine  Autophagy  Apoptosis  Ros  Nsclc  
Efficacy and Mechanisms of Chinese Medicine on the Modulation of Myocardial Autophagy in Cardiovascular Disease Journal article
American Journal of Chinese Medicine, 2017,Volume: 45,Issue: 5,Page: 917–932
作者:  Li, Yue-Ying;  Zhao, Yong-Hua
收藏  |  浏览/下载:2/0  |  提交时间:2019/01/18
Autophagy  Cardiovascular Disease  Chinese Medicines  Review