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The phosphodiesterase-4 inhibitor, FCPR16, attenuates ischemia-reperfusion injury in rats subjected to middle cerebral artery occlusion and reperfusion Journal article
BRAIN RESEARCH BULLETIN, 2018,Volume: 137,Page: 98-106
Authors:  Chen, Jiajia;  Yu, Hui;  Zhong, Jiahong;  Feng, Hongfang;  Wang, Haitao;  Cheng, Yufang;  Zou, Zhengqiang;  Huang, Chang;  Zhou, Zhongzhen;  Zheng, Wenhua;  Xu, Jiangping
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PDE4 inhibitor  FCPR16  Ischemia-reperfusion injury  Stroke  Apoptosis  Inflammation  
Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-kappa B Inhibition Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2017,Volume: 362,Issue: 1,Page: 67-77
Authors:  Zou, Zheng-Qiang;  Chen, Jia-Jia;  Feng, Hong-Fang;  Cheng, Yu-Fang;  Wang, Hai-Tao;  Zhou, Zhong-Zhen;  Guo, Hai-Biao;  Zheng, Wenhua;  Xu, Jiang-Ping
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The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 5,Page: 3395-3406
Authors:  Zeng, Zhiwen;  Wang, Xue;  Bhardwaj, Sanjeev K.;  Zhou, Xuanhe;  Little, Peter J.;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
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Schizophrenia  Clozapine  Corticosterone  Pi3k/akt/foxo3a  Neuroprotection  
Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3 beta and the ERK Pathway Journal article
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2017,Volume: 37,Issue: 4,Page: 655-664
Authors:  Yu, Jie;  Zheng, Jiacheng;  Lin, Jiajia;  Jin, Linlu;  Yu, Rui;  Mak, Shinghung;  Hu, Shengquan;  Sun, Hongya;  Wu, Xiang;  Zhang, Zaijun;  Lee, Mingyuen;  Tsim, Wahkeung;  Su, Wei;  Zhou, Wenhua;  Cui, Wei;  Han, Yifan;  Wang, Qinwen
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Indirubin-3-oxime  H2O2  GSK3 beta  PI3-K  ERK