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Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells Journal article
NATURE COMMUNICATIONS, 2018,Volume: 9
Authors:  Wu, Changjie;  Lyu, Junfang;  Yang, Eun Ju;  Liu, Yifan;  Zhang, Baoyuan;  Shim, Joong Sup
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite  |  View/Download:11/0  |  Submit date:2018/12/17
Effects of insulin on transcriptional response and permeability in an in vitro model of human blood-brain barrier Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2018,Volume: 119,Issue: 7,Page: 5657-5664
Authors:  Kuai, Ziyu;  Xu, Yan;  Zhao, Qi;  Liu, Jie;  Guan, Shanshan;  Qiao, Yongbo;  Gong, Xin;  Nie, Jiaojiao;  Li, Pengju;  Liu, Dongni;  Xing, Yifan;  Li, Huiwen;  Sun, Zixiao;  Wang, Wenqi;  Ning, Chunan;  Shi, Yuhua;  Kong, Wei;  Shan, Yaming
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Alzheimer's Disease  Human Blood-brain Barrier  Insulin  Type 2 Diabetes  Transcriptional Response  Permeability  
Research and development of anti-Alzheimer's disease drugs: an update from the perspective of technology flows Journal article
EXPERT OPINION ON THERAPEUTIC PATENTS, 2018,Volume: 28,Issue: 4,Page: 341-350
Authors:  Liu, Kunmeng;  Lin, Hui-Heng;  Pi, Rongbiao;  Mak, Shinghung;  Han, Yifan;  Hu, Yuanjia
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31
Alzheimer's disease  patent  technology flow  citation network  research and development  
Research and development of anti-Alzheimer's disease drugs: an update from the perspective of technology flows Journal article
EXPERT OPINION ON THERAPEUTIC PATENTS, 2018,Volume: 28,Issue: 4,Page: 341-350
Authors:  Liu, Kunmeng;  Lin, Hui-Heng;  Pi, Rongbiao;  Mak, Shinghung;  Han, Yifan;  Hu, Yuanjia
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31
Alzheimer's disease  patent  technology flow  citation network  research and development  
Research and development of anti-Alzheimer's disease drugs: an update from the perspective of technology flows Journal article
EXPERT OPINION ON THERAPEUTIC PATENTS, 2018,Volume: 28,Issue: 4,Page: 341-350
Authors:  Liu, Kunmeng;  Lin, Hui-Heng;  Pi, Rongbiao;  Mak, Shinghung;  Han, Yifan;  Hu, Yuanjia
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Alzheimer's disease  patent  technology flow  citation network  research and development  
PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A Journal article
CANCER LETTERS, 2018,Volume: 436,Page: 28-37
Authors:  Liu, Yifan;  Yang, Eun Ju;  Zhang, Baoyuan;  Miao, Zhengqiang;  Wu, Changjie;  Lyu, Junfang;  Tan, Kaeling;  Poon, Terence Chuen Wai;  Shim, Joong Sup
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Akt  Kw2449  Synthetic Lethality  Aurka  Drug Combination  
Research and development of anti-Alzheimer's disease drugs: an update from the perspective of technology flows Journal article
EXPERT OPINION ON THERAPEUTIC PATENTS, 2018,Volume: 28,Issue: 4,Page: 341-350
Authors:  Liu, Kunmeng;  Lin, Hui-Heng;  Pi, Rongbiao;  Mak, Shinghung;  Han, Yifan;  Hu, Yuanjia
Favorite  |  View/Download:7/0  |  Submit date:2018/10/30
Alzheimer's disease  patent  technology flow  citation network  research and development  
Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018,Volume: 14,Issue: 10,Page: 1175-1185
Authors:  Lyu, Junfang;  Yang, Eun Ju;  Head, Sarah A.;  Ai, Nana;  Zhang, Baoyuan;  Wu, Changjie;  Li, Ruo-Jing;  Liu, Yifan;  Chakravarty, Harapriya;  Zhang, Shaolin;  Tam, Kin Yip;  Dang, Yongjun;  Kwon, Ho Jeong;  Gel, Wei;  Liu, Jun O.;  Shim, Joong Sup
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Cholesterol Trafficking  Angiogenesis  Astemizole  Npc1  Mtor  
Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth Journal article
CANCER LETTERS, 2017,Volume: 409,Page: 91-103
Authors:  Lyu, Junfang;  Yang, Eun Ju;  Head, Sarah A.;  Ai, Nana;  Zhang, Baoyuan;  Wu, Changjie;  Li, Ruo-Jing;  Liu, Yifan;  Yang, Chen;  Dang, Yongjun;  Kwon, Ho Jeong;  Ge, Wei;  Liu, Jun O.;  Shim, Joong Sup
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Cholesterol Trafficking  Angiogenesis  Tumor  Lysosome  Cepharanthine