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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:258/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite | View/Download:75/0 | TC[WOS]:0 TC[Scopus]:3 | Submit date:2020/09/16
BRCA1  Breast cancer  DNA damage  HDAC  Histone deacetylase  Reactive oxygen species  Synthetic lethality  
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:74/0 | TC[WOS]:2 TC[Scopus]:6 | Submit date:2020/09/16
ATM-AMPK-DRP1  BRCA1  inflammasomes  mitochondrial dynamics  mitophagy  
Andrographolide derivative ameliorates dextran sulfate sodium-induced experimental colitis in mice Journal article
BIOCHEMICAL PHARMACOLOGY, 2019,Volume: 163,Page: 416-424
Authors:  Bao-Jian Guo;  Zhuyun Liu;  Mo-Yu Ding;  Feng Li;  Mei Jing;  Li-Peng Xu;  Yu-Qiang Wang;  Zai-Jun Zhang;  Yitao Wang;  Decai Wang;  Guo-Chun Zhou;  Ying Wang
Favorite | View/Download:19/0 | TC[WOS]:2 TC[Scopus]:3 | Submit date:2020/03/27
Andrographolide Analog  Colitis  Ibd  Nf-κb  Β-catenin  
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy Journal article
Human molecular genetics, 2018
Authors:  Xiaoling Xu;  Eric Chen;  Lihua Mo;  Lei Zhang;  Fangyuan Shao;  Kai Miao;  Jianlin Liu;  Sek Man Su;  Monica Valecha;  Un In Chan;  Hongping Zheng;  Mark Chen;  Weiping Chen;  Qiang Chen;  Haiqing Fu;  Mirit I. Aladjem;  Yanzhen He;  Chu-Xia Deng
Favorite | View/Download:45/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2018/12/17
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite | View/Download:32/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date:2018/12/17
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
View | Adobe PDF | Favorite | View/Download:530/14 | TC[WOS]:7 TC[Scopus]:16 | Submit date:2018/10/30
FOXC1 is associated with estrogen receptor and affects sensitivity of tamoxifen treatment in breast cancer Conference paper
Authors:  Wang, Jin-hua;  Xu, Ya-li;  Chen, Xiu-ping;  Li, Li;  Wang, Lin;  Yao, Ru;  Sun, Qiang;  Du, Guan-hua
Favorite | View/Download:9/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/10/30
breast cancer  estrogen receptor  FOXC1  TCGA  triple negative  
Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-kappa B Inhibition Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2017,Volume: 362,Issue: 1,Page: 67-77
Authors:  Zou, Zheng-Qiang;  Chen, Jia-Jia;  Feng, Hong-Fang;  Cheng, Yu-Fang;  Wang, Hai-Tao;  Zhou, Zhong-Zhen;  Guo, Hai-Biao;  Zheng, Wenhua;  Xu, Jiang-Ping
Favorite | View/Download:25/0 | TC[WOS]:12 TC[Scopus]:16 | Submit date:2018/10/30
Draft genome of the lined seahorse, Hippocampus erectus Journal article
GIGASCIENCE, 2017,Volume: 6,Issue: 6
Authors:  Lin, Qiang;  Qiu, Ying;  Gu, Ruobo;  Xu, Meng;  Li, Jia;  Bian, Chao;  Zhang, Huixian;  Qin, Geng;  Zhang, Yanhong;  Luo, Wei;  Chen, Jieming;  You, Xinxin;  Fan, Mingjun;  Sun, Min;  Xu, Pao;  Venkatesh, Byrappa;  Xu, Junming;  Fu, Hongtuo;  Shi, Qiong
Favorite | View/Download:31/0 | TC[WOS]:14 TC[Scopus]:14 | Submit date:2018/10/30
genome  assembly  annotation  Hippocampus erectus