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Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9 Journal article
NATURE METHODS, 2019,Volume: 16,Issue: 8,Page: 722–730
Authors:  Gigi C. G. Choi;  Peng Zhou;  Chaya T. L. Yuen;  Becky K. C. Chan;  Feng Xu;  Siyu Bao;  Hoi Yee Chu;  Dawn Thean;  Kaeling Tan;  Koon Ho Wong;  Zongli Zheng;  Alan S. L. Wong
Favorite | View/Download:16/0 | TC[WOS]:4 TC[Scopus]:11 | Submit date:2020/05/21
Universal plasmids to facilitate gene deletion and gene tagging in filamentous fungi Journal article
FUNGAL GENETICS AND BIOLOGY, 2019,Volume: 125,Page: 28-35
Authors:  Longguang Qin;  Ang Li;  Kaeling Tan;  Shuhui Guo;  Yingying Chen;  Fang Wang;  Koon Ho Wong
Favorite | View/Download:8/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/21
Gene Deletion  Epitope Tagging  Selectable Markers  Plasmid Collection  Filamentous Fungi  Aspergillus  
A genome-wide analysis of carbon catabolite repression in Schizosaccharomyces pombe Journal article
BMC GENOMICS, 2019,Volume: 20
Authors:  Dane Vassiliadis;  Koon Ho Wong;  Alex Andrianopoulos;  Brendon J. Monahan
Favorite | View/Download:15/0 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2020/06/12
Schizosaccharomyces Pombe  Transcriptional Regulation  Carbon Metabolism  Carbon Catabolite Repression  Rst2  Rna-seq  Chip-seq Background  Tup11  Scr1  
Requirements for RNA polymerase II preinitiation complex formation in vivo Journal article
ELIFE, 2019,Volume: 8
Authors:  Natalia Petrenko;  Yi Jin;  Liguo Dong;  Koon Ho Wong;  Kevin Struhl
Favorite | View/Download:10/0 | TC[WOS]:2 TC[Scopus]:7 | Submit date:2020/06/12
Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance Journal article
MBIO, 2019,Volume: 10,Issue: 1
Authors:  Sang Hu Kim;  Kali R. Iyer;  Lakhansing Pardeshi;  José F. Muñoz;  Nicole Robbins;  Christina A. Cuomo;  Koon Ho Wong;  Leah E. Cowen
Favorite | View/Download:14/0 | TC[WOS]:13 TC[Scopus]:24 | Submit date:2020/06/12
Antifungal Drug Resistance  Candida Albicans  Candida Auris  Cdr1  Developmental Program  Emerging Pathogen  Fungal Morphogenesis  Fungal Pathogen  Hsp90  Transcriptional Program  
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite | View/Download:32/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date:2018/12/17
Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 22,Page: 8315-8329
Authors:  Sun, Heng;  Miao, Zhengqiang;  Zhang, Xin;  Chan, Un In;  Su, Sek Man;  Guo, Sen;  Wong, Chris Koon Ho;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite | View/Download:60/0 | TC[WOS]:6 TC[Scopus]:9 | Submit date:2018/10/30
Mammary Gland  Development  Breast Cancer  Biomarker  Cell Differentiation  Stem Cells  cdh5+cell  Mammary Stem Cells (Mascs)  Single Cell Rna-seq  
Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia Journal article
Journal of Biological Chemistry, 2018,Volume: 293,Issue: 22
Authors:  Sun,Heng;  Miao,Zhengqiang;  Zhang,Xin;  Chan,Un In;  Su,Sek Man;  Guo,Sen;  Wong,Chris Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:7/0 | TC[WOS]:6 TC[Scopus]:9 | Submit date:2020/09/16
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space Journal article
PLOS GENETICS, 2018,Volume: 14,Issue: 3
Authors:  Veri, Amanda O.;  Miao, Zhengqiang;  Shapiro, Rebecca S.;  Tebbji, Faiza;  O'Meara, Teresa R.;  Kim, Sang Hu;  Colazo, Juan;  Tan, Kaeling;  Vyas, Valmik K.;  Whiteway, Malcolm;  Robbins, Nicole;  Wong, Koon Ho;  Cowen, Leah E.
Favorite | View/Download:52/0 | TC[WOS]:11 TC[Scopus]:13 | Submit date:2018/10/30
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation Journal article
NATURE COMMUNICATIONS, 2017,Volume: 8
Authors:  Xie, Jinglin L.;  Qin, Longguang;  Miao, Zhengqiang;  Grys, Ben T.;  Diaz, Jacinto De La Cruz;  Ting, Kenneth;  Krieger, Jonathan R.;  Tong, Jiefei;  Tan, Kaeling;  Leach, Michelle D.;  Ketela, Troy;  Moran, Michael F.;  Krysan, Damian J.;  Boone, Charles;  Andrews, Brenda J.;  Selmecki, Anna;  Wong, Koon Ho;  Robbins, Nicole;  Cowen, Leah E.
Favorite | View/Download:26/0 | TC[WOS]:16 TC[Scopus]:22 | Submit date:2018/10/30