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Discrimination of three Siegesbeckiae Herba species using UPLC-QTOF/MS-based metabolomics approach Conference paper
FOOD AND CHEMICAL TOXICOLOGY, Kunming, PEOPLES R CHINA, AUG 25-30, 2018
Authors:  Tao, Hong-Xun;  Xiong, Wei;  Zhao, Guan-Ding;  Peng, Yu;  Zhong, Zhang-Feng;  Xu, Liang;  Duan, Ran;  Tsim, Karl W. K.;  Yu, Hua;  Wang, Yi-Tao
Favorite | View/Download:47/0 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/10/30
Metabolomics  Traditional Chinese Medicines  Multi-origin Herbs  Siegesbeckiae Herba Species  Uplc-qtof/ms  
Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway Journal article
Cellular and Molecular Neurobiology, 2017,Volume: 37,Issue: 4,Page: 655-664
Authors:  Yu J.;  Zheng J.;  Lin J.;  Jin L.;  Yu R.;  Mak S.;  Hu S.;  Sun H.;  Wu X.;  Zhang Z.;  Lee M.;  Tsim W.;  Su W.;  Zhou W.;  Cui W.;  Han Y.;  Wang Q.
Favorite | View/Download:10/0 | TC[WOS]:10 TC[Scopus]:0 | Submit date:2018/11/06
ERK  GSK3β  H2O2  Indirubin-3-oxime  PI3-K  
Robust Neuritogenesis-Promoting Activity by Bis(heptyl)-Cognitin Through the Activation of alpha7-Nicotinic Acetylcholine Receptor/ERK Pathway Journal article
CNS Neuroscience and Therapeutics, 2015,Volume: 21,Issue: 6,Page: 520-529
Authors:  Hu S.-Q.;  Cui W.;  Mak S.-H.;  Choi C.-L.;  Hu Y.-J.;  Li G.;  Tsim K.W.-K.;  Pang Y.-P.;  Han Y.-F.
Favorite | View/Download:8/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/12/28
Alpha7-nicotinic Acetylcholine Receptor  Bis(Heptyl)-cognitin  Extracellular Signal-regulated Kinase  Neurite Outgrowth  Neurodegenerative Disorders  
Inhibiting β-Amyloid-Associated Alzheimer’s Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue Journal article
Journal of Molecular Neuroscience, 2015,Volume: 55,Issue: 4,Page: 1014
Authors:  Hu S.;  Wang R.;  Cui W.;  Zhang Z.;  Mak S.;  Xu D.;  Choi C.;  Tsim K.W.;  Carlier P.R.;  Lee M.;  Han Y.
Favorite | View/Download:4/0 | TC[WOS]:13 TC[Scopus]:0 | Submit date:2018/10/30
Alzheimer’s disease  Aβ fibrils  Bis(12)-hupyridone  Cell viability  Memory impairment  Thioflavin T  
Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β Journal article
Journal of Molecular Neuroscience, 2015,Volume: 57,Issue: 4,Page: 561–570
Authors:  Hu S.;  Cui W.;  Zhang Z.;  Mak S.;  Xu D.;  Li G.;  Hu Y.;  Wang Y.;  Lee M.;  Tsim K.W.;  Han Y.
Favorite | View/Download:8/0 | TC[WOS]:16 TC[Scopus]:0 | Submit date:2018/10/30
6ohda  Gsk3β  Indirubin-3-oxime  Mef2d  Neuroprotection  Parkinson’s Disease  
Sunitinib produces neuroprotective effect via inhibiting nitric oxide overproduction Journal article
CNS Neuroscience and Therapeutics, 2014,Volume: 20,Issue: 3,Page: 244-252
Authors:  Cui W.;  Zhang Z.-J.;  Hu S.-Q.;  Mak S.-H.;  Xu D.-P.;  Choi C.-L.;  Wang Y.-Q.;  Tsim W.-K.;  Lee M.-Y.;  Rong J.-H.;  Han Y.-F.
Favorite | View/Download:10/0 | TC[WOS]:26 TC[Scopus]:0 | Submit date:2018/11/06
Cancer  Neuroprotection  Nitric Oxide  Nitric Oxide Synthase  Receptor Tyrosine Kinase  Sunitinib  
Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons Journal article
JOURNAL OF PROTEOME RESEARCH, 2007,Volume: 6,Issue: 7,Page: 2435-2446
Authors:  Hongjun Fu;  Wenming Li;  Yulin Liu;  Yuanzhi Lao;  Wei Liu;  Cheng Chen;  Hua Yu;  Nelson T. K. Lee;  Donald C. Chang;  Peng Li;  Yuanping Pang;  Karl W. K. Tsim;  Mingtao Li;  Yifan Han
Favorite | View/Download:70/0 | TC[WOS]:26 TC[Scopus]:0 | Submit date:2020/03/12
Bis(7)-tacrine  Glutamate  Mitochondria  Cerebellar Granule Neurons  Two-dimensional Differential In-gel Electrophoresis  Maldi-tof/ms