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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:76/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite | View/Download:74/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
BRCA1  Breast cancer  DNA damage  HDAC  Histone deacetylase  Reactive oxygen species  Synthetic lethality  
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space Journal article
PLOS GENETICS, 2018,Volume: 14,Issue: 3
Authors:  Veri, Amanda O.;  Miao, Zhengqiang;  Shapiro, Rebecca S.;  Tebbji, Faiza;  O'Meara, Teresa R.;  Kim, Sang Hu;  Colazo, Juan;  Tan, Kaeling;  Vyas, Valmik K.;  Whiteway, Malcolm;  Robbins, Nicole;  Wong, Koon Ho;  Cowen, Leah E.
Favorite | View/Download:49/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/10/30
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation Journal article
NATURE COMMUNICATIONS, 2017,Volume: 8
Authors:  Xie, Jinglin L.;  Qin, Longguang;  Miao, Zhengqiang;  Grys, Ben T.;  Diaz, Jacinto De La Cruz;  Ting, Kenneth;  Krieger, Jonathan R.;  Tong, Jiefei;  Tan, Kaeling;  Leach, Michelle D.;  Ketela, Troy;  Moran, Michael F.;  Krysan, Damian J.;  Boone, Charles;  Andrews, Brenda J.;  Selmecki, Anna;  Wong, Koon Ho;  Robbins, Nicole;  Cowen, Leah E.
Favorite | View/Download:24/0 | TC[WOS]:16 TC[Scopus]:0 | Submit date:2018/10/30