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Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models Journal article
Cell Death and Disease, 2020,Volume: 11,Issue: 2
Authors:  Zhuang，Xu Xu;  Wang，Sheng Fang;  Tan，Yuan;  Song，Ju Xian;  Zhu，Zhou;  Wang，Zi Ying;  Wu，Ming Yue;  Cai，Cui Zan;  Huang，Zhi Jian;  Tan，Jie Qiong;  Su，Huan Xing;  Li，Min;  Lu，Jia Hong
Favorite | View/Download：0/0 | TC[WOS]:8 TC[Scopus]:10 | Submit date：2021/03/01
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation Journal article
Autophagy, 2020
Authors:  Cai，Cui Zan;  Yang，Chuanbin;  Zhuang，Xu Xu;  Yuan，Ning Ning;  Wu，Ming Yue;  Tan，Jie Qiong;  Song，Ju Xian;  Cheung，King Ho;  Su，Huanxing;  Wang，Yi Tao;  Tang，Bei Sha;  Behrends，Christian;  Durairajan，Siva Sundara Kumar;  Yue，Zhenyu;  Li，Min;  Lu，Jia Hong
Favorite | View/Download：0/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date：2021/03/01
Amaturation  Autophagy  CCZ1-MON1A  NRBF2  PI3KC3/VPS34  RAB7  trafficking  
Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation Journal article
Phytomedicine, 2019,Volume: 61
Authors:  Cai，Cui Zan;  Zhou，He Feng;  Yuan，Ning Ning;  Wu，Ming Yue;  Lee，Simon Ming Yuen;  Ren，Jiao Yan;  Su，Huan Xing;  Lu，Jin Jian;  Chen，Xiu Ping;  Li，Min;  Tan，Jie Qiong;  Lu，Jia Hong
Favorite | View/Download：0/0 | TC[WOS]:6 TC[Scopus]:7 | Submit date：2021/03/01
-synuclein  Harmine  Parkinson's disease  Protein kinase A  Ubiquitin-proteasome system  
High content screening for drug discovery from traditional Chinese medicine Journal article
Chinese Medicine (United Kingdom), 2019,Volume: 14,Issue: 1
Authors:  Wang，Jing;  Wu，Ming Yue;  Tan，Jie Qiong;  Li，Min;  Lu，Jia Hong
Favorite | View/Download：0/0 | TC[WOS]:3 TC[Scopus]:6 | Submit date：2021/03/02
Advanced models  Drug discovery  High-content screening  Progressive instruments  Traditional Chinese medicine  
Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology Journal article
FRONTIERS IN PHARMACOLOGY, 2019
Authors:  Ning-Ning Yuan;  Cui-Zan Cai;  Ming-Yue Wu;  Qi Zhu;  HuanXing Su;  Min Li;  JiaoYan Ren;  Jie-Qiong Tan;  Jia-Hong Lu
Favorite | View/Download：33/0 | TC[WOS]:4 TC[Scopus]:6 | Submit date：2020/04/14
Canthin-6-one  Parkinson’s Disease  Alpha-synuclein  Ubiquitin-proteasome-system  Crispr/cas9  Rpn2/psmd1  Pka  
Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 44,Page: 77673-77684
Authors:  Wu, Ming-Yue;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Tan, Jie-Qiong;  Li, Min;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Wang, Yi-Tao;  Zheng, Wei;  Lu, Jia-Hong
Favorite | View/Download：44/0 | TC[WOS]:9 TC[Scopus]:13 | Submit date：2018/10/30
Dauricine  Daurisoline  Autophagy Blocker  Cancer Cells  Cell Toxicity  
NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models Journal article
AUTOPHAGY, 2017,Volume: 13,Issue: 12,Page: 2028-2040
Authors:  Yang, Chuanbin;  Cai, Cui-Zan;  Song, Ju-Xian;  Tan, Jie-Qiong;  Durairajan, Siva Sundara Kumar;  Iyaswamy, Ashok;  Wu, Ming-Yue;  Chen, Lei-Lei;  Yue, Zhenyu;  Li, Min;  Lu, Jia-Hong
Favorite | View/Download：39/0 | TC[WOS]:23 TC[Scopus]:24 | Submit date：2018/10/30
a Beta  Alzheimer's Disease  App  Autophagy  Class Iii Phosphatidylinositol 3-kinase (Ptdins3k)  Nrbf2  
BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage Journal article
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017
Authors:  Qin, Li-Xia;  Tan, Jie-qiong;  Zhang, Hai-nan;  Rizwana, Kousar;  Lu, Jia-hong;  Tang, Jian-guang;  Jiang, Bo;  Shen, Xiang-min;  Guo, Ji-feng;  Tang, Bei-sha;  Tan, Li-ming;  Wang, Chun-yu
Favorite | View/Download：42/0 | TC[WOS]:7 TC[Scopus]:11 | Submit date：2018/10/30