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Nagilactone E suppresses TGF-β1-induced epithelial–mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
Phytomedicine, 2019,Volume: 52,Page: 32-39
Authors:  Zhang L.-L.;  Jiang X.-M.;  Huang M.-Y.;  Feng Z.-L.;  Chen X.;  Wang Y.;  Li H.;  Li A.;  Lin L.-G.;  Lu J.-J.
Favorite  |  View/Download:10/0  |  Submit date:2018/12/28
Epithelial-mesenchymal transition  Nagilactone E  Smad  TGF-β1  
Combination of Salvia miltiorrhiza and ligustrazine attenuates bleomycin-induced pulmonary fibrosis in rats via modulating TNF-alpha and TGF-beta Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Huang, Chengliang;  Wu, Xu;  Wang, Shengpeng;  Wang, Wenjun;  Guo, Fang;  Chen, Yuanyuan;  Pan, Bi;  Zhang, Ming;  Fan, Xianming
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Ligustrazine  Pulmonary fibrosis  Salvia miltiorrhiza  SMAD4  TNF-alpha  
The role of TGF-β/SMAD4 signaling in cancer Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 2,Page: 111-123
Authors:  Zhao M.;  Mishra L.;  Deng C.-X.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/13
Mouse Model  Prognosis  Smad4  Tgf-β  Tumorigenesis  
Partial müllerian duct retention in Smad4 conditional mutant male mice Journal article
International Journal of Biological Sciences, 2016,Volume: 12,Issue: 6,Page: 667-676
Authors:  Petit F.G.;  Deng C.;  Jamin S.P.
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Conditional Knockout  Müllerian Duct  Smad4  Β-catenin  
The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 8,Page: 956
Authors:  Rostam M.A.;  Kamato D.;  Piva T.J.;  Zheng W.;  Little P.J.;  Osman N.
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Atherosclerosis  Glycosaminoglycan  Signalling  Smad  Transforming growth factor-β  Vascular smooth muscle  
Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 1,Page: 110-119
Authors:  Kamato D.;  Thach L.;  Getachew R.;  Burch M.;  Hollenberg M.D.;  Zheng W.;  Little P.J.;  Osman N.
Favorite  |  View/Download:0/0  |  Submit date:2018/12/21
Glycosaminoglycan enzymes  Smad linker region  Thrombin  Transactivation-dependent  Transforming growth factor β  
Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development Journal article
Developmental Biology, 2015,Volume: 398,Issue: 2,Page: 231-241
Authors:  Lane J.;  Yumoto K.;  Azhar M.;  Ninomiya-Tsuji J.;  Inagaki M.;  Hu Y.;  Deng C.-X.;  Kim J.;  Mishina Y.;  Kaartinen V.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/13
Palatogenesis  Smad4  Tak1  Tgf-β3 Signaling  Trim33  
Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells Journal article
The Journal of pharmacy and pharmacology, 2014,Volume: 66,Issue: 12,Page: 1722-1733
Authors:  Kamato D.;  Rostam M.A.;  Piva T.J.;  Babaahmadi Rezaei H.;  Getachew R.;  Thach L.;  Bernard R.;  Zheng W.;  Little P.J.;  Osman N.
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cell signalling  serine/threonine kinase  Smad linker region  Smads  transforming growth factor-β  
3,3′-Diindolylmethane ameliorates experimental hepatic fibrosis via inhibiting miR-21 expression Journal article
British Journal of Pharmacology, 2013,Volume: 170,Issue: 3,Page: 649-660
Authors:  Zhang Z.;  Gao Z.;  Hu W.;  Yin S.;  Wang C.;  Zang Y.;  Chen J.;  Zhang J.;  Dong L.
Favorite  |  View/Download:9/0  |  Submit date:2018/11/07
3,3′-diindolylmethane  Ap-1  Hepatic Stellate Cells  Liver Fibrosis  Mir-21  Smad  Tgf-β  
(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1026-1036
Authors:  Kamato D.;  Babaahmadi Rezaei H.;  Getachew R.;  Thach L.;  Guidone D.;  Osman N.;  Roufogalis B.;  Duke C.C.;  Tran V.H.;  Zheng W.;  Little P.J.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/21
(S)-[6]-Gingerol  biglycan  proteoglycans  Smad signalling