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Targeted Delivery of a Ligand−Drug Conjugate via Formyl Peptide Receptor 1 through Cholesterol-Dependent Endocytosis Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 6,Page: 2636-2647
作者:  Junlin Wang;  Meiwan Chen;  Shaoping Li;  Richard D. Ye
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/07
g Protein-coupled Receptors  Ph-sensitive Peptides Conjugates  Formyl Peptides  Receptor Internalization  Targeted Drug Delivery  
In vitro immunomodulatory effects of human milk oligosaccharides on murine macrophage RAW264.7 cells Journal article
CARBOHYDRATE POLYMERS, 2019,Volume: 207,Page: 230-238
作者:  Zhang, Weiyue;  Yan, Jingyu;  Wu, Lehao;  Yu, Yang;  Ye, Richard D.;  Zhang, Yan;  Liang, Xinmiao
收藏  |  浏览/下载:4/0  |  提交时间:2019/01/17
Human milk oligosaccharides  Immunomodulator  Nitric oxide  Cytokine  NF-kappa B  MAPKs  
A Role for MK2 in Enhancing Neutrophil-Derived ROS Production and Aggravating Liver schemia/Reperfusion Injury Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
作者:  Sun, Lei;  Wu, Qiong;  Nie, Yunjuan;  Cheng, Ni;  Wang, Rui;  Wang, Gang;  Zhang, Dan;  He, Huiqiong;  Ye, Richard D.;  Qian, Fang
收藏  |  浏览/下载:4/0  |  提交时间:2019/01/17
MK2  ROS  p47(phox)  neutrophils  hepatic ischemia/reperfusion injury  
FAM19A1 is a new ligand for GPR1 that modulates neural stem-cell proliferation and differentiation Journal article
FASEB JOURNAL, 2018,Volume: 32,Issue: 11,Page: 5874-5890
作者:  Zheng, Can;  Chen, Dixin;  Zhang, Yan;  Bai, Yun;  Huang, Shiyang;  Zheng, Danfeng;  Liang, Weiwei;  She, Shaoping;  Peng, Xinjian;  Wang, Pingzhang;  Mo, Xiaoning;  Song, Quansheng;  Lv, Ping;  Huang, Jing;  Ye, Richard D.;  Wang, Ying
收藏  |  浏览/下载:31/0  |  提交时间:2018/10/31
neural stem cell  GPCR  cytokines  
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
作者:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
浏览  |  Adobe PDF(2278Kb)  |  收藏  |  浏览/下载:175/3  |  提交时间:2018/10/30
acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
作者:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
浏览  |  Adobe PDF(2092Kb)  |  收藏  |  浏览/下载:135/10  |  提交时间:2018/10/30
acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
Elevated Expression of Serum Amyloid A 3 Protects Colon Epithelium Against Acute Injury Through TLR2-Dependent Induction of Neutrophil IL-22 Expression in a Mouse Model of Colitis Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
作者:  Zhang, Gufang;  Liu, Jin;  Wu, Lehao;  Fang, Yu;  Sun, Lei;  Qian, Feng;  Chen, Daijie;  Ye, Richard D.
收藏  |  浏览/下载:13/0  |  提交时间:2018/10/30
serum amyloid A  inflammation  innate immunity  cytokines  colitis  neutrophils  
4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists Journal article
BIOCHEMICAL PHARMACOLOGY, 2017,Volume: 142,Page: 120-132
作者:  Kirpotina, Liliya N.;  Schepetkin, Igor A.;  Khlebnikov, Andrei I.;  Ruban, Olga I.;  Ge, Yunjun;  Ye, Richard D.;  Kominsky, Douglas J.;  Quinn, Mark T.
收藏  |  浏览/下载:19/0  |  提交时间:2018/10/30
Antagonist Formyl peptide receptor  1H-pyrrol-2(5H)-one  Neutrophil  Molecular modeling  
4 '-Hydroxywogonin suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages and acute lung injury mice Journal article
PLOS ONE, 2017,Volume: 12,Issue: 8
作者:  Fan, Chao;  Wu, Le-Hao;  Zhang, Gu-Fang;  Xu, Fangfang;  Zhang, Shuo;  Zhang, Xiuli;  Sun, Lei;  Yu, Yang;  Zhang, Yan;  Ye, Richard D.
收藏  |  浏览/下载:11/0  |  提交时间:2018/10/30
Suppression of Lipopolysaccharide-Induced Inflammatory Response by Fragments from Serum Amyloid A Journal article
JOURNAL OF IMMUNOLOGY, 2017,Volume: 199,Issue: 3,Page: 1105-1112
作者:  Zhou, Huibin;  Chen, Mingjie;  Zhang, Gufang;  Ye, Richard D.
收藏  |  浏览/下载:12/0  |  提交时间:2018/10/30