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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:257/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite | View/Download:75/0 | TC[WOS]:0 TC[Scopus]:2 | Submit date:2020/09/16
BRCA1  Breast cancer  DNA damage  HDAC  Histone deacetylase  Reactive oxygen species  Synthetic lethality  
A comparative study for determinants of gaming performance in Macao and Las Vegas Journal article
Tourism Management, 2020,Volume: 77
Authors:  Qiang Deng;  Xinhua Gu;  Rob Law;  Zhaotong Lian
Favorite | View/Download:589/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2019/11/11
Dea  Sur  Gaming Efficiency  Casino Tourism  Resort Hospitality  
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:74/0 | TC[WOS]:2 TC[Scopus]:6 | Submit date:2020/09/16
ATM-AMPK-DRP1  BRCA1  inflammasomes  mitochondrial dynamics  mitophagy  
The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment Journal article
EBioMedicine, 2020,Volume: 51
Authors:  Hou,Weilong;  Chen,Qiang;  Wang,Haitao;  Qiu,Pengxiang;  Lyu,Xueying;  Chen,Weiping;  Chua,Melvin L.K.;  Chinn,Y. Eugene;  Deng,Chu Xia;  Wang,Ruihong
Favorite | View/Download:74/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
Adipogenesis  Apoptosis  Ceramide  Epigenetic modification  Metabolic landscape  Metabolomics  Obesity  
Multifunctional two-dimensional semiconductors SnP3: universal mechanism of layer-dependent electronic phase transition Journal article
JOURNAL OF PHYSICS-CONDENSED MATTER, 2018,Volume: 30,Issue: 47
Authors:  Gong, Peng-Lai;  Zhang, Fang;  Huang, Liang-Feng;  Zhang, Hu;  Li, Liang;  Xiao, Rui-Chun;  Deng, Bei;  Pan, Hui;  Shi, Xing-Qiang
Favorite | View/Download:18/0 | TC[WOS]:7 TC[Scopus]:7 | Submit date:2019/01/17
Metal-to-semiconductor Transition  Lone-pair Electrons  Two-dimensional Snp3  
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy Journal article
Human molecular genetics, 2018
Authors:  Xiaoling Xu;  Eric Chen;  Lihua Mo;  Lei Zhang;  Fangyuan Shao;  Kai Miao;  Jianlin Liu;  Sek Man Su;  Monica Valecha;  Un In Chan;  Hongping Zheng;  Mark Chen;  Weiping Chen;  Qiang Chen;  Haiqing Fu;  Mirit I. Aladjem;  Yanzhen He;  Chu-Xia Deng
Favorite | View/Download:45/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2018/12/17
Receptor mediated transcytosis in biological barrier: The influence of receptor character and their ligand density on the transmembrane pathway of active-targeting nanocarriers Journal article
BIOMATERIALS, 2018,Volume: 180,Page: 78-90
Authors:  Xiaoning Song;  Rui Li;  Hailiang Deng;  Ye Li;  Yanan Cui;  Hua Zhang;  Wenbing Dai;  Bing He;  Ying Zheng;  Xueqing Wang;  Qiang Zhang
Favorite | View/Download:33/0 | TC[WOS]:10 TC[Scopus]:0 | Submit date:2018/10/30
Nanocarriers  Caco-2 Cell Monolayer  Receptor Character  Ligand Density  Intracellular Transport  Transcytosis  
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite | View/Download:32/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date:2018/12/17
Chemical characterization and immunomodulatory activity of acetylated polysaccharides from Dendrobium devonianum Journal article
CARBOHYDRATE POLYMERS, 2018,Volume: 180,Page: 238-245
Authors:  Deng, Yong;  Li, Min;  Chen, Ling-Xiao;  Chen, Xian-Qiang;  Lu, Jia-Hong;  Zhao, Jing;  Li, Shao-Ping
Favorite | View/Download:42/0 | TC[WOS]:17 TC[Scopus]:22 | Submit date:2018/10/30
Dendrobium Devonianum  Chain Conformation  Saccharide Mapping  Immunomodulatory Activity