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Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite  |  View/Download:6/0  |  Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Emerging Screening Approaches in the Development of Nrf2-Keap1 Protein-Protein Interaction Inhibitors Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019,Volume: 20,Issue: 18
Authors:  Leung, CH;  Zhang, JT;  Yang, GJ;  Liu, H;  Han, QB;  Ma, DL
Favorite  |  View/Download:3/0  |  Submit date:2020/03/23
Virtual Screening  Keap1-nrf2  Protein-protein Interaction  Inhibitors  Oxidative Stress  
Engineered delivery strategies for enhanced control of growth factor activities in wound healing Journal article
Advanced Drug Delivery Reviews, 2018
Authors:  Yiming Niu;  Qiu Li;  Ya Ding;  Lei Dong;  Chunming Wang
Favorite  |  View/Download:18/0  |  Submit date:2018/11/30
Biomaterials Scaffolds  Controlled Delivery System  Skin Tissue Regeneration  Molecular Engineering  Extracellular Matrix  Glycosaminoglycan-protein Interaction  Therapeutic Angiogenesis  
Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery Journal article
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2018,Volume: 11
Authors:  Li, Ting;  Jiang, Hu-Lin;  Tong, Yun-Guang;  Lu, Jin-Jian
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
Hsp90 Chaperone Machinery  Cdc37  Kinase Client  Protein Interaction  
Granulin-epithelin precursor interacts with 78-kDa glucose-regulated protein in hepatocellular carcinoma Journal article
BMC CANCER, 2017,Volume: 17
Authors:  Chi Wai Yip;  Ching Yan Lam;  Terence C. W. Poon;  Tan To Cheung;  Phyllis F. Y. Cheung;  Sze Wai Fung;  Xiao Qi Wang;  Idy C. Y. Leung;  Linda W. C. Ng;  Chung Mau Lo;  George S. W. Tsao;  Siu Tim Cheung
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
Granulin-epithelin Precursor  78-kda Glucose-regulated Protein  Hepatocellular Carcinoma  Mass Spectrometry  Protein Interaction  
An analysis of evolutionary conservation based on genomic orthology and protein-protein interaction networks Book chapter
出自: Biotechnology in Hong Kong Volume III, Whitestone, New York:United State-China Itelletual Property Institute Inc, 2017, 页码: 49-60
Authors:  Hui Hens Lin;  Pengpeng Li;  Xiangjun Kong;  Jing Cai;  Shibing Su;  Yuanjia Hu;  Hui Hens Lin;  Pengpeng Li;  Xiangjun Kong;  Jing Cai;  Shibing Su;  Yuanjia Hu
Favorite  |  View/Download:13/0  |  Submit date:2019/01/14
Protein-protein Interaction Networks  Evolutionary Conservation  Orthologs  
Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds Journal article
Oncotarget, 2016,Volume: 7,Issue: 12,Page: 13965
Authors:  Liu L.-J.;  He B.;  Miles J.A.;  Wang W.;  Mao Z.;  Che W.I.;  Lu J.-J.;  Chen X.-P.;  Wilson A.J.;  Ma D.-L.;  Leung C.-H.
Favorite  |  View/Download:7/0  |  Submit date:2018/10/30
Hdm2  Metal-based Inhibitor  P53  Protein-protein Interaction  
Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 38-43
Authors:  Leung K.-H.;  Liu L.-J.;  Lin S.;  Lu L.;  Zhong H.-J.;  Susanti D.;  Rao W.;  Wang M.;  Che W.I.;  Chan D.S.H.;  Leung C.-H.;  Chan P.W.H.;  Ma D.-L.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/06
Pharmacophore  Protein-protein interaction  STAT3  Virtual screening  
Rfa2 is specifically dephosphorylated by Pph3 in Candida albicans Journal article
Biochemical Journal, 2013,Volume: 449,Issue: 3,Page: 673-681
Authors:  Wang H.;  Gao J.;  Wong A.H.-H.;  Hu K.;  Li W.;  Wang Y.;  Sang J.
Favorite  |  View/Download:9/0  |  Submit date:2019/01/16
Dephosphorylation  Dna Replication  Phosphatase  Protein-dna Interaction  Replication Protein a (Rpa)  
Interaction of dietary polyphenols with bovine milk proteins: Molecular structure-affinity relationship and influencing bioactivity aspects Journal article
Molecular Nutrition and Food Research, 2011,Volume: 55,Issue: 11,Page: 1637-1645
Authors:  Xiao J.;  Mao F.;  Yang F.;  Zhao Y.;  Zhang C.;  Yamamoto K.
Favorite  |  View/Download:5/0  |  Submit date:2019/01/15
DPPH radical scavengers  Milk proteins  Polyphenols  Protein-polyphenol interaction  Structure-affinity relationship