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Alarmone Ap4A is elevated by aminoglycoside antibiotics and enhances their bactericidal activity Journal article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019,Volume: 116,Issue: 19,Page: 9578-9585
Authors:  Xia Ji;  Jin Zou;  Haibo Peng;  Anne-Sophie Stolle;  Ruiqiang Xie;  Hongjie Zhang;  Bo Peng;  John J. Mekalanos;  Jun Zheng
Favorite | View/Download:14/0 | TC[WOS]:13 TC[Scopus]:12 | Submit date:2020/05/19
Antibiotic Action  Aminoglycoside  Kanamycin  Diadenosine  Tetraphosphate Ap4a  Alarmone  
Central role of autophagic UVRAG in melanogenesis and the suntan response Journal article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018,Volume: 115,Issue: 33,Page: E7728-E7737
Authors:  Yang, Yongfei;  Jang, Gyu-beom;  Yang, Xuanjun;  Wang, Qiaoxiu;  He, Shanshan;  Li, Shun;  Quach, Christine;  Zhao, Shihui;  Li, Fan;  Yuan, Zengqiang;  Lee, Hye-Ra;  Zhong, Hanbing;  Liang, Chengyu
Favorite | View/Download:27/0 | TC[WOS]:11 TC[Scopus]:13 | Submit date:2018/10/30
UVRAG  MITF  BLOC-1  melanosome  BRAF  
Antagonistic actions of juvenile hormone and 20-hydroxyecdysone within the ring gland determine developmental transitions in Drosophila Journal article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018,Volume: 115,Issue: 1,Page: 139-144
Authors:  Liu, Suning;  Li, Kang;  Gao, Yue;  Liu, Xi;  Chen, Weiting;  Ge, Wei;  Feng, Qili;  Palli, Subba R.;  Li, Sheng
Favorite | View/Download:36/0 | TC[WOS]:42 TC[Scopus]:43 | Submit date:2018/10/30
Juvenile Hormone  20-hydroxyecdysone  Ring Gland  Hormone Biosynthesis  Antagonistic Action  
Structural basis of kindlin-mediated integrin recognition and activation Journal article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017,Volume: 114,Issue: 35,Page: 9349-9354
Authors:  Li, Huadong;  Deng, Yi;  Sun, Kang;  Yang, Haibin;  Liu, Jie;  Wang, Meiling;  Zhang, Zhang;  Lin, Jirong;  Wu, Chuanyue;  Wei, Zhiyi;  Yu, Cong
Favorite | View/Download:29/0 | TC[WOS]:64 TC[Scopus]:61 | Submit date:2018/10/30
kindlin  fermitin  FERMT2  Mig-2  integrin signaling  
Lability of secondary organic particulate matter Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2016,Volume: 113,Issue: 45,Page: 12643-12648
Authors:  Liu P.;  Li Y.J.;  Wang Y.;  Gilles M.K.;  Zaveri R.A.;  Bertram A.K.;  Martin S.T.
Favorite | View/Download:10/0 | TC[WOS]:60 TC[Scopus]:62 | Submit date:2018/10/30
Atmospheric Chemistry  Secondary Organic Aerosol  Evaporation  
The antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015,Volume: 112,Issue: 52,Page: E7276-E7285
Authors:  Sarah A. Head;  Wei Shi;  Liang Zhao;  Kirill Gorshkov;  Kalyan Pasunooti;  Yue Chen;  Zhiyou Deng;  Ruo-jing Li;  Joong Sup Shim;  Wenzhi Tan;  Thomas Hartung;  Jin Zhang;  Yingming Zhao;  Marco Colombini;  Jun O. Liu
Favorite | View/Download:12/0 | TC[WOS]:50 TC[Scopus]:50 | Submit date:2019/01/24
Angiogenesis  Mitochondria  Metabolism  Itraconazole  Vdac1  
Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2015,Volume: 112,Issue: 52,Page: E7276
Authors:  Head S.A.;  Shi W.;  Zhao L.;  Gorshkov K.;  Pasunooti K.;  Chen Y.;  Deng Z.;  Li R.-J.;  Shim J.S.;  Tan W.;  Hartung T.;  Zhang J.;  Zhao Y.;  Colombini M.;  Liu J.O.
Favorite | View/Download:12/0 | TC[WOS]:50 TC[Scopus]:50 | Submit date:2018/10/30
Angiogenesis  Itraconazole  Metabolism  Mitochondria  VDAC1  
Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2011,Volume: 108,Issue: 48,Page: 19264-19269
Authors:  Rovira M.;  Huang W.;  Yusuff S.;  Shim J.S.;  Ferrante A.A.;  Liu J.O.;  Parsons M.J.
Favorite | View/Download:7/0 | TC[WOS]:65 TC[Scopus]:67 | Submit date:2019/01/15
Development  Embryogenesis  Notch-signaling  Progenitor  
Extensive divergence of yeast stress responses through transitions between induced and constitutive activation Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2011,Volume: 108,Issue: 40,Page: 16693-16698
Authors:  Tirosh I.;  Wong K.H.;  Barkai N.;  Struhl K.
Favorite | View/Download:13/0 | TC[WOS]:24 TC[Scopus]:27 | Submit date:2019/01/16
Biological Function  Evolutionary Conservation  Functional Evolution  Gene Regulation  
Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2010,Volume: 107,Issue: 31,Page: 13818-13823
Authors:  Li H.;  He C.;  Feng J.;  Zhang Y.;  Tang Q.;  Bian Z.;  Bai X.;  Zhou H.;  Jiang H.;  Heximer S.P.;  Qin M.;  Huang H.;  Liu P.P.;  Huang C.
Favorite | View/Download:15/0 | TC[WOS]:96 TC[Scopus]:98 | Submit date:2018/12/28
Erk1/2  Mek1/2  Rgs5  Signal Transduction