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Metabolic characterization of (±)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 90,Issue: 5,Page: 98-110
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Yan, Ru;  Wang, Yi-Tao
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(+/-)-praeruptorin a  Metabolism  Lightsight (Tm) Software  In Vivo  Peucedani Radix  
H-1 nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 93,Issue: SI,Page: 86-94
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Chen, Yan-Gan;  Yuan, Yun-Fei;  Yan, Ru;  Wang, Yi-Tao
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Peucedani Radix  Metabolomic Profile  Quantitative H-1 Nmr  Praeruptorin a  Praeruptorin b  
1H nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2014,Volume: 93,Page: 86-94
Authors:  Song Y.-L.;  Jing W.-H.;  Chen Y.-G.;  Yuan Y.-F.;  Yan R.;  Wang Y.-T.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/28
Metabolomic profile  Peucedani Radix  Praeruptorin A  Praeruptorin B  
1H nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2014,Volume: 93,Page: 86-94
Authors:  Song Y.-L.;  Jing W.-H.;  Chen Y.-G.;  Yuan Y.-F.;  Yan R.;  Wang Y.-T.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/06
Metabolomic profile  Peucedani Radix  Praeruptorin A  Praeruptorin B  
Regulation of human pregnane X receptor and its target gene cytochrome P450 3A by praeruptorin a isolated from the herbal medicine peucedanum praeruptorum Journal article
Planta Medica, 2013,Volume: 79,Issue: 16,Page: 1509-1515
Authors:  Huang L.;  Bi H.-C.;  Li Y.-H.;  Zhang J.-Q.;  Kuang S.-Y.;  Zhang L.;  Wang Y.-T.;  Huang M.
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Apiaceae  Cytochrome P450 3a  Herb-drug Interaction  Peucedanum Praeruptorum  Praeruptorin a  Pregnane x Receptor  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupl Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013,Volume: 77,Page: 175-188
Authors:  Jing, Wang-Hui;  Song, Yue-Lin;  Yan, Ru;  Wang, Yi-Tao
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Angular-type Pyranocoumarins  (+)-praeruptorin a  Uhplc-qt-ms/ms  Human Liver Microsomes  Cyp 3a4  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2013,Volume: 77,Page: 175
Authors:  Jing W.-H.;  Song Y.-L.;  Yan R.;  Wang Y.-T.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31
(+)-praeruptorin a  Angular-type Pyranocoumarins  Cyp 3a4  Human Liver Microsomes  Uhplc-qt-ms/ms  
Up-regulatation of CYP3A expression through pregnent X receptor by praeruptorin D isolated from Peucedanum praeruptorum Dunn Journal article
Journal of Ethnopharmacology, 2013,Volume: 148,Issue: 2,Page: 596
Authors:  Huang L.;  Huang M.;  Li Y.-H.;  Li R.-M.;  Zeng Y.;  Kuang S.-Y.;  Zhang L.;  Wang Y.-T.;  Bi H.-C.
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Praeruptorin d Pregnane x Receptor (Pxr) Cytochrome P450 3a Induction Herb-drug Interaction  
Transport and metabolism of (±)-praeruptorin A in Caco-2 cell monolayers Journal article
Xenobiotica, 2011,Volume: 41,Issue: 1,Page: 71
Authors:  Jing W.H.;  Song Y.L.;  Yan R.;  Bi H.C.;  Li P.T.;  Wang Y.T.
Favorite  |  View/Download:13/0  |  Submit date:2018/10/31
(±)-praeruptorin a  Caco-2 Cells  Enantioselectivity  Hydrolysis  Metabolism  Transport