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MLKL mediates apoptosis via a mutual regulation with PERK/eIF2 alpha pathway in response to reactive oxygen species generation Journal article
APOPTOSIS, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Wen‑Xiang Cao;  Ting Li;  Zheng‑Hai Tang;  Le‑Le Zhang;  Zhao‑Yu Wang;  Xia Guo;  Min‑Xia Su;  Xiuping Chen;  Jin‑Jian Lu
Favorite  |  View/Download:5/0  |  Submit date:2020/01/09
Mlkl  Eif2α  Ros  Apoptosis  Chelerythrine  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:338/27  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018,Volume: 14,Issue: 10,Page: 1389-1398
Authors:  Tan, Qiaoyan;  Wang, Zuqiang;  Wang, Quan;  Wang, Yuanqiang;  Huang, Zhifeng;  Su, Nan;  Jin, Min;  Kuang, Liang;  Qi, Huabing;  Ni, Zhenhong;  Li, Can;  Zhu, Ying;  Jiang, Wanling;  Chen, Hangang;  Deng, Chuxia;  Du, Xiaolan;  Xie, Yangli;  Chen, Lin
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Phage Display  Fgfr1  Peptide  Cancer Therapy  Lung Cancer  
Investigational Hypoxia-Activated Prodrugs: Making Sense of Future Development Journal article
Current Drug Targets, 2018,Volume: 20
Authors:  Min-Xia Su;  Le-Le Zhang;  Zhang-Jian Huang;  Jia-Jie Shi;  Jin-Jian Lu
Favorite  |  View/Download:5/0  |  Submit date:2019/01/14
Hypoxia-activated Prodrug  Topoisomerase Ii Inhibitors  Dna Alkylating Agents  Targeted Drugs  Reductases Activity  Patient Selection  Clinical Progress  
Osimertinib (AZD9291) decreases programmed death ligand-1 in EGFR-mutated non-small cell lung cancer cells Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 11,Page: 1512-1520
Authors:  Jiang, Xiao-Ming;  Xu, Yu-Lian;  Huang, Mu-Yang;  Zhang, Le-Le;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Non-small Cell Lung Cancer  Egfr  Osimertinib  Pd-l1  Ubiquitin-proteasome System  Mg-132  Bortezomib  Gsk3 Beta  Licl  
Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation Journal article
JOURNAL OF BONE AND MINERAL RESEARCH, 2017,Volume: 32,Issue: 11,Page: 2194-2206
Authors:  Xu, Wei;  Luo, Fengtao;  Wang, Quan;  Tan, Qiaoyan;  Huang, Junlan;  Zhou, Siru;  Wang, Zuqiang;  Sun, Xianding;  Kuang, Liang;  Jin, Min;  Su, Nan;  Jiang, Wanling;  Chen, Liang;  Qi, Huabing;  Zhu, Ying;  Chen, Bo;  Chen, Hangang;  Chen, Shuai;  Gao, Yu;  Xu, Xiaoling;  Deng, Chuxia;  Chen, Lin;  Xie, Yangli;  Du, Xiaolan
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Bone Marrow Ablation  Fgfr2  Bone Formation  Wnt/beta-catenin  
Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell lung cancer cells Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 321,Page: 18-26
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Osimertinib  Azd9291  Autophagy  Apoptosis  Ros