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An Integrated Transfer Learning and Multitask Learning Approach for Pharmacokinetic Parameter Prediction Journal article
Molecular Pharmaceutics, 2019,Volume: 16,Issue: 2,Page: 533-541
Authors:  Ye Z.;  Yang Y.;  Li X.;  Cao D.;  Ouyang D.
Favorite  |  View/Download:7/0  |  Submit date:2019/02/14
ADME  deep learning  multitask learning  pharmacokinetic parameters  transfer learning  
Transdermal Cubic Phases of Metformin Hydrochloride: In Silico and in Vitro Studies of Delivery Mechanisms Journal article
MOLECULAR PHARMACEUTICS, 2018,Volume: 15,Issue: 8,Page: 3121-3132
Authors:  Yu, Xiang;  Jin, Yiguang;  Du, Lina;  Sun, Mengchi;  Wang, Jian;  Li, Qiu;  Zhang, Xiangyu;  Gao, Zisen;  Ding, Pingtian
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
computational simulation  cubic phase  dissipative particle dynamics  metformin hydrochloride  molecular interaction  transdermal delivery  
Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System Journal article
MOLECULAR PHARMACEUTICS, 2018,Volume: 15,Issue: 4,Page: 1664-1673
Authors:  Zhao, Qianqian;  Miriyala, Nikhila;  Su, Yan;  Chen, Weijie;  Gao, Xuejiao;  Shao, Ling;  Yan, Ru;  Li, Haifeng;  Yao, Xiaojun;  Cao, Dongsheng;  Wang, Yitao;  Ouyang, Defang
View  |  Adobe PDF(4697Kb)  |  Favorite  |  View/Download:160/19  |  Submit date:2018/10/30
Lutein  Cyclodextrin  Multiple-component System  Molecular Dynamics Simulation  Bioavailability  Computer-aided Formulation Design  
Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy Journal article
MOLECULAR PHARMACEUTICS, 2017,Volume: 14,Issue: 11,Page: 3644-3659
Authors:  Zhang, Jinming;  Zheng, Yifeng;  Xie, Xi;  Wang, Lan;  Su, Ziren;  Wang, Yitao;  Leong, Kam W.;  Chen, Meiwan
View  |  Adobe PDF(2484Kb)  |  Favorite  |  View/Download:180/34  |  Submit date:2018/10/30
Tumor-targeting  Glycyrrhetinic Acid  Ph-sensitive  Tat Exposure  Mixed Micelles  
Pluronic P85/F68 Micelles of Baicalein Could Interfere with Mitochondria to Overcome MRP2-Mediated Efflux and Offer Improved Anti-Parkinsonian Activity Journal article
Molecular Pharmaceutics, 2017,Volume: 14,Issue: 10,Page: 3331-3342
Authors:  Chen T.;  Li Y.;  Li C.;  Yi X.;  Wang R.;  Lee S.M.-Y.;  Zheng Y.
Favorite  |  View/Download:4/0  |  Submit date:2018/11/06
Baicalein  Fluorescence Resonance Energy Transfer (Fret)  Micelles  Mitochondria  Multidrug Resistance-associated Protein 2 (Mrp2)  Neuroprotective Effect  
Pluronic P85/F68 Micelles of Baicalein Could Interfere with Mitochondria to Overcome MRP2-Mediated Efflux and Offer Improved Anti-Parkinsonian Activity Journal article
MOLECULAR PHARMACEUTICS, 2017,Volume: 14,Issue: 10,Page: 3331-3342
Authors:  Chen, Tongkai;  Li, Ye;  Li, Chuwen;  Yi, Xiang;  Wang, Ruibing;  Lee, Simon Ming-Yuen;  Zheng, Ying
Favorite  |  View/Download:7/0  |  Submit date:2018/10/30
micelles  baicalein  fluorescence resonance energy transfer (FRET)  multidrug resistance-associated protein 2 (MRP2)  mitochondria  neuroprotective effect  
Oral delivery of a nanocrystal formulation of schisantherin a with improved bioavailability and brain delivery for the treatment of Parkinson's disease Journal article
Molecular Pharmaceutics, 2016,Volume: 13,Issue: 11,Page: 3864-3875
Authors:  Chen T.;  Li C.;  Li Y.;  Yi X.;  Lee S.M.-Y.;  Zheng Y.
Favorite  |  View/Download:4/0  |  Submit date:2018/11/06
Brain Delivery  Dissolution  Nanocrystals  Oral Bioavailability  Parkinson's Disease (Pd)  
A redox-sensitive and RAGE-targeting nanocarrier for hepatocellular carcinoma therapy Journal article
Molecular Pharmaceutics, 2016,Volume: 13,Issue: 11,Page: 3613-3625
Authors:  Fang X.-B.;  Xu Y.-Q.;  Chan H.-F.;  Wang C.-M.;  Zheng Q.;  Xiao F.;  Chen M.-W.
Favorite  |  View/Download:12/0  |  Submit date:2018/11/07
Hcc  Oridonin  Pluronic F68  Rage  Redox-sensitivity  
Codelivery of Doxorubicin and shAkt1 by Poly(ethylenimine)-Glycyrrhetinic Acid Nanoparticles to Induce Autophagy-Mediated Liver Cancer Combination Therapy Journal article
Molecular Pharmaceutics, 2016,Volume: 13,Issue: 4,Page: 1298-1307
Authors:  Wang F.-Z.;  Xing L.;  Tang Z.-H.;  Lu J.-J.;  Cui P.-F.;  Qiao J.-B.;  Jiang L.;  Jiang H.-L.;  Zong L.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/28
Autophagy  Combination Therapy  Glycyrrhetinic Acid  Liver Cancer Targeting  Self-assembled  
Glycyrrhetinic Acid Mediated Drug Delivery Carriers for Hepatocellular Carcinoma Therapy Journal article
Molecular Pharmaceutics, 2016,Volume: 13,Issue: 3,Page: 699
Authors:  Cai Y.;  Xu Y.;  Chan H.F.;  Fang X.;  He C.;  Chen M.
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Anti-hcc  Delivery Systems  Ga  Liver-targeting