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MLKL mediates apoptosis via a mutual regulation with PERK/eIF2 alpha pathway in response to reactive oxygen species generation Journal article
APOPTOSIS, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Cao, Wen-Xiang;  Li, Ting;  Tang, Zheng-Hai;  Zhang, Le-Le;  Wang, Zhao-Yu;  Guo, Xia;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
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MLKL  eIF2 alpha  ROS  Apoptosis  Chelerythrine  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
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EMT  ERK1  2  lung cancer  Snail  toosendanin  
The Bone-Protecting Efficiency of Chinese Medicines Compared With Western Medicines in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of Comparative Studies Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Cai, Xiao;  Chen, Xiu-Min;  Xia, Xuan;  Bao, Kun;  Wang, Rong-Rong;  Peng, Jian-Hong;  Liu, Hai-Jun;  Yang, Qiao-Wen;  Yan, Jing-Yao;  Wang, Mao-Jie;  Yu, Hua;  Lu, Jin-Jian;  Hu, Yuan-Jia;  Jakobsson, Per-Johan;  Wen, Ze-Huai;  Huang, Run-Yue;  Huang, Qing-Chun
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Rheumatoid Arthritis (RA)  Chinese medicine  bone-protecting efficiency  systematic review  meta-analysis  
A novel design of a polynuclear co-delivery system for safe and efficient cancer therapy Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 63,Page: 8737-8740
Authors:  Xing, Lei;  Zhang, Jia-Liang;  Zhou, Tian-Jiao;  He, Yu-Jing;  Cui, Peng-Fei;  Gong, Jia-Hui;  Sun, Minjie;  Lu, Jin-Jian;  Huang, Zhangjian;  Jin, Liang;  Jiang, Hu-Lin
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Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
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Nagilactone E  Non-small cell lung cancer  Cyclin B1  Cell cycle  Apoptosis  
Anticancer drug discovery from Chinese medicinal herbs Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Huang, Mu-Yang;  Zhang, Le-Le;  Ding, Jian;  Lu, Jin-Jian
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Chinese medicinal herbs  Anticancer  Drug discovery  Natural products  Formulae  
Diethyl Blechnic, a Novel Natural Product Isolated from Salvia miltiorrhiza Bunge, Inhibits Doxorubicin-Induced Apoptosis by Inhibiting ROS and Activating JNK1/2 Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018,Volume: 19,Issue: 6
Authors:  Yu, Jie;  Gao, Hongwei;  Wu, Chuanhong;  Xu, Qiong-Ming;  Lu, Jin-Jian;  Chen, Xiuping
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diethyl blechnic  DOX  cardiotoxicity  ROS  JNK1  2  
Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery Journal article
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2018,Volume: 11
Authors:  Li, Ting;  Jiang, Hu-Lin;  Tong, Yun-Guang;  Lu, Jin-Jian
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Hsp90 chaperone machinery  Cdc37  Kinase client  Protein interaction  
Synthesis and Evaluation of O-2-Derived Diazeniumdiolates Activatable via Bioorthogonal Chemistry Reactions in Living Cells Journal article
ORGANIC LETTERS, 2018,Volume: 20,Issue: 8,Page: 2164-2167
Authors:  Lv, Tian;  Wu, Jianbing;  Kang, Fenghua;  Wang, Tingting;  Wan, Boheng;  Lu, Jin-Jian;  Zhang, Yihua;  Huang, Zhangjian
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Novel biflavonoids from Cephalotaxus oliveri Mast. Journal article
PHYTOCHEMISTRY LETTERS, 2018,Volume: 24,Page: 150-153
Authors:  Ren, Dai;  Meng, Fan-Cheng;  Liu, Hui;  Xiao, Tong;  Lu, Jin-Jian;  Lin, Li-Gen;  Chen, Xiu-Ping;  Zhang, Qing-Wen
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Cephalotaxus oliveri  Biflavonoid  Flavonoid  Alkaloid  Umcephabiflovin  alpha-Glucosidase inhibitory effect