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Tanshinone IIA attenuates insulin like growth factor 1-induced cell proliferation in PC12 cells through the PI3K/Akt and MEK/ERK pathways Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 9
Authors:  Wang H.;  Su X.;  Fang J.;  Xin X.;  Zhao X.;  Gaur U.;  Wen Q.;  Xu J.;  Little P.J.;  Zheng W.
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Akt  Antiproliferation  ERK  IGF-1R  Tanshinone IIA  
Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.;  Getachew R.;  Cao Y.;  Zheng W.;  Osman N.;  Little P.J.
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Role of brain-derived neurotrophic factor and nerve growth factor in the regulation of Neuropeptide W in vitro and in vivo Journal article
Molecular and Cellular Endocrinology, 2017,Volume: 447,Page: 71-78
Authors:  Wang R.;  Yan F.;  Liao R.;  Wan P.;  Little P.J.;  Zheng W.
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HPA axis  Neuropeptide W  Neurotrophins  PI3K/Akt  
Elucidating the role of the FoxO3a transcription factor in the IGF-1-induced migration and invasion of uveal melanoma cancer cells Journal article
Biomedicine and Pharmacotherapy, 2016,Volume: 84,Page: 1538-1550
Authors:  Yan F.;  Liao R.;  Farhan M.;  Wang T.;  Chen J.;  Wang Z.;  Little P.J.;  Zheng W.
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FoxO3a translocation  IGF-1  Metastases  Uveal melanoma  
Multiple growth factors, but not VEGF, stimulate glycosaminoglycan hyperelongation in retinal choroidal endothelial cells Journal article
International Journal of Biological Sciences, 2016,Volume: 12,Issue: 9,Page: 1041-1051
Authors:  Al Gwairi O.;  Osman N.;  Getachew R.;  Zheng W.;  Liang X.-L.;  Kamato D.;  Thach L.;  Little P.J.
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Age related macular degeneration  Bruch's membrane  Growth factors  Proteoglycans  VEGF  Xyloside  
Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response Journal article
Journal of Pharmacy and Pharmacology, 2016,Volume: 68,Issue: 3,Page: 368-378
Authors:  Bernard R.;  Getachew R.;  Kamato D.;  Thach L.;  Osman N.;  Chan V.;  Zheng W.;  Little P.J.
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cell signalling  GAG hyperelongation  platelet derived growth factor  proteoglycan  tinibs  transforming growth factor-β  
The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 8,Page: 956
Authors:  Rostam M.A.;  Kamato D.;  Piva T.J.;  Zheng W.;  Little P.J.;  Osman N.
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Atherosclerosis  Glycosaminoglycan  Signalling  Smad  Transforming growth factor-β  Vascular smooth muscle  
Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 1,Page: 110-119
Authors:  Kamato D.;  Thach L.;  Getachew R.;  Burch M.;  Hollenberg M.D.;  Zheng W.;  Little P.J.;  Osman N.
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Glycosaminoglycan enzymes  Smad linker region  Thrombin  Transactivation-dependent  Transforming growth factor β  
Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways Journal article
Psychopharmacology, 2016,Volume: 233,Issue: 5,Page: 785
Authors:  Zeng Z.;  Wang H.;  Shang F.;  Zhou L.;  Little P.J.;  Quirion R.;  Zheng W.
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Apoptosis  Lithium  Neuroprotection  Pi3k/akt/foxo1  Serum Deprivation  
Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling Journal article
British Journal of Pharmacology, 2016,Volume: 173,Issue: 20,Page: 2992-3000
Authors:  Little P.J.;  Hollenberg M.D.;  Kamato D.;  Thomas W.;  Chen J.;  Wang T.;  Zheng W.;  Osman N.
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