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Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018,Volume: 14,Issue: 10,Page: 1175-1185
Authors:  Lyu, Junfang;  Yang, Eun Ju;  Head, Sarah A.;  Ai, Nana;  Zhang, Baoyuan;  Wu, Changjie;  Li, Ruo-Jing;  Liu, Yifan;  Chakravarty, Harapriya;  Zhang, Shaolin;  Tam, Kin Yip;  Dang, Yongjun;  Kwon, Ho Jeong;  Gel, Wei;  Liu, Jun O.;  Shim, Joong Sup
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Cholesterol Trafficking  Angiogenesis  Astemizole  Npc1  Mtor  
Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth Journal article
CANCER LETTERS, 2017,Volume: 409,Page: 91-103
Authors:  Lyu, Junfang;  Yang, Eun Ju;  Head, Sarah A.;  Ai, Nana;  Zhang, Baoyuan;  Wu, Changjie;  Li, Ruo-Jing;  Liu, Yifan;  Yang, Chen;  Dang, Yongjun;  Kwon, Ho Jeong;  Ge, Wei;  Liu, Jun O.;  Shim, Joong Sup
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Cholesterol Trafficking  Angiogenesis  Tumor  Lysosome  Cepharanthine  
Development of an angiogenesis-focused cDNA chip and validation of its functionality Journal article
EXPERIMENTAL AND MOLECULAR MEDICINE, 2005,Volume: 37,Issue: 4,Page: 365-370
Authors:  Joong Sup Shim;  Hae Kwang Lee;  Hyo Mi Park;  Jong Ok Kim;  Eun Kyung Kim;  Kyung Hoon Hwang;  Ki Tae Kim;  Seong-Whan Park;  Je Hyeon Lee;  Ho Jeong Kwon
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Angiogenesis  Dna Chip  Duplicate Spots  Gene Expression Profile  Histone Deacetylase  
A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function Journal article
CHEMISTRY & BIOLOGY, 2004,Volume: 11,Issue: 10,Page: 1455-1463
Authors:  Joong Sup Shim;  Jiyong Lee;  Hyun-Ju Park;  So-Jung Park;  Ho Jeong Kwon
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Chemical genetics for therapeutic target mining Journal article
EXPERT OPINION ON THERAPEUTIC TARGETS, 2004,Volume: 8,Issue: 6,Page: 653-661
Authors:  Joong Sup Shim;  Ho Jeong Kwon
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Angiogenesis  Chemical Genetics  Functional Genomics  Target Identification  
Psammaplin A, a marine natural product, inhibits aminopeptidase N and suppresses angiogenesis in vitro Journal article
CANCER LETTERS, 2004,Volume: 203,Issue: 2,Page: 163-169
Authors:  Joong Sup Shim;  Hyi-Seung Lee;  Jongheon Shin;  Ho Jeong Kwon
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Psammaplin a  Aminopeptidase n  Chemoinvasion  Angiogenesis  
Plakoglobin is a new target gene of histone deacetylase in human fibrosarcoma HT1080 cells Journal article
ONCOGENE, 2004,Volume: 23,Issue: 9,Page: 1704-1711
Authors:  Joong Sup Shim;  Dong Hoon Kim;  Ho Jeong Kwon
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Histone Deacetylase  Transcriptional Repression  Plakoglobin  Oncogene  
Irreversible inhibition of CD13/aminopeptidase N by the anti-angiogenic agent curcumin Journal article
CHEMISTRY & BIOLOGY, 2003,Volume: 10,Issue: 8,Page: 695-704
Authors:  Joong Sup Shim;  Jin Hee Kim;  Hyun Young Cho;  Young Na Yum;  Seung Hee Kim;  Hyun-Ju Park;  Bum Sang Shim;  Seung Hoon Choi;  Ho Jeong Kwon
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