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Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer Journal article
SCIENTIFIC REPORTS, 2018,Volume: 8
Authors:  Lyu, Peng;  Ge, Lilin;  Ma, Rui;  Wei, Ran;  McCrudden, Cian M.;  Chen, Tianbao;  Shaw, Chris;  Kwok, Hang Fai
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer Journal article
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018,Volume: 22,Issue: 9,Page: 4097-4105
Authors:  Wei, Ran;  Wong, Janet Pik Ching;  Lyu, Peng;  Xi, Xinping;  Tong, Olivia;  Zhang, Shu-Dong;  Yuen, Hiu Fung;  Shirasawa, Senji;  Kwok, Hang Fai
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
Colorectal Cancer  Connectivity Mapping  Osteopontin  Survival  
Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide Journal article
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018,Volume: 22,Issue: 9,Page: 4460-4473
Authors:  Li, Bin;  Lyu, Peng;  Xi, Xinping;  Ge, Lilin;  Mahadevappa, Ravikiran;  Shaw, Chris;  Kwok, Hang Fai
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Anticancer Mechanism  Binding Sites  Ms  Ms Proteome  Ngs Transcriptome  Signalling Pathways  Venom Library  
Does size matter? Venom proteomic and functional comparison between night adder species (Viperidae: Causus) with short and long venom glands Journal article
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2018,Volume: 211,Page: 7-14
Authors:  Coimbra, Francisco C. P.;  Dobson, James;  Zdenek, Christina N.;  op den Brouw, Bianca;  Hamilton, Brett;  Debono, Jordan;  Masci, Paul;  Frank, Nathaniel;  Ge, Lilin;  Kwok, Hang Fai;  Fry, Bryan G.
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The Roles of Protein Tyrosine Phosphatases in Hepatocellular Carcinoma Journal article
CANCERS, 2018,Volume: 10,Issue: 3,Page: 82
Authors:  Huang, Yide;  Zhang, Yafei;  Ge, Lilin;  Lin, Yao;  Kwok, Hang Fai
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Protein-tyrosine Phosphatase Inhibitors  Hepatocellular Carcinoma  Signaling Pathways  Therapeutic Targets  
Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis) Journal article
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2018,Volume: 205,Page: 53-61
Authors:  Goldenberg, Jonathan;  Cipriani, Vittoria;  Jackson, Timothy N. W.;  Arbuckle, Kevin;  Debono, Jordan;  Dashevsky, Daniel;  Panagides, Nadya;  Ikonomopoulou, Maria P.;  Koludarov, Ivan;  Li, Bin;  Santana, Renan Castro;  Nouwens, Amanda;  Jones, Alun;  Hay, Chris;  Dunstan, Nathan;  Allen, Luke;  Bush, Brian;  Miles, John J.;  Ge, Lilin;  Kwok, Hang Fai;  Fry, Bryan G.
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Venom Evolution  Pseudechis  Black Snakes  Diet  Toxins  Proteomic  Enzymology  Oxyuraninae  Pla(2)  
Anti-tumor effects of a 'human & mouse cross-reactive' anti-ADAM17 antibody in a pancreatic cancer model in vivo Conference paper
Authors:  Ye, Jie;  Yuen, Shun Ming;  Murphy, Gillian;  Xie, Ruiyu;  Kwok, Hang Fai
Favorite  |  View/Download:5/0  |  Submit date:2018/10/31
Pancreatic ductal adenocarcinoma (PDAC)  ADAM17  Inhibitory antibody  Tumorigenesis  Targeted therapy  
The Roles of microRNAs in Regulating the Expression of PD-1/PD-L1 Immune Checkpoint Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017,Volume: 18,Issue: 12
Authors:  Wang, Qingshui;  Lin, Wei;  Tang, Xiaoqiong;  Li, Suhuan;  Guo, Libin;  Lin, Yao;  Kwok, Hang Fai
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Programmed Death-ligand 1 (Pd-l1)  Programmed Death 1(Pd-1)  Micrornas  Immune Checkpoint  
Venom-based peptide therapy: insights into anti-cancer mechanism Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 59,Page: 100908-100930
Authors:  Ma, Rui;  Mahadevappa, Ravikiran;  Kwok, Hang Fai
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Anticancer Mechanism  Venom  Metastasis  Targeted Therapy  Signaling Pathway  
Venom Peptides: Improving Specificity in Cancer Therapy Journal article
TRENDS IN CANCER, 2017,Volume: 3,Issue: 9,Page: 611-614
Authors:  Mahadevappa, Ravikiran;  Ma, Rui;  Kwok, Hang Fai
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30