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Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca2+-Activated K+ Channels (BKCa) Journal article
Evidence-based Complementary and Alternative Medicine, 2016,Volume: 2016
Authors:  Tseng H.H.L.;  Vong C.T.;  Leung G.P.-H.;  Seto S.W.;  Kwan Y.W.;  Lee S.M.-Y.;  Hoi M.P.M.
Favorite | View/Download:6/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/11/06
Relaxation effect of a novel Danshensu/tetramethylpyrazine derivative on rat mesenteric arteries Journal article
European Journal of Pharmacology, 2015,Volume: 761,Page: 153-160
Authors:  Li R.W.-S.;  Yang C.;  Shan L.;  Zhang Z.;  Wang Y.;  Kwan Y.W.;  Lee S.M.Y.;  Hoi M.P.M.;  Chan S.W.;  Cheung A.C.;  Cheung K.H.;  Leung G.P.H.
Favorite | View/Download:11/0 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2018/11/06
Calcium Channel  Danshensu Tetramethylpyrazine  Mesenteric Artery  Relaxation  
Basal Flt1 tyrosine kinase activity is a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis Journal article
Biochimica et Biophysica Acta - General Subjects, 2015,Volume: 1850,Issue: 2,Page: 373-384
Authors:  Li S.;  Zhou X.L.;  Dang Y.Y.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.-Y.;  Hoi M.P.M.
Favorite | View/Download:8/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/11/06
Calycosin  Endothelial Cell  Flt1  Molecular Docking  Vegf Receptor Inhibitor  Zebrafish  
VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation Journal article
Toxicology and Applied Pharmacology, 2014,Volume: 280,Issue: 3,Page: 408-420
Authors:  Li S.;  Dang Y.Y.;  Oi Lam Che G.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.Y.;  Hoi M.P.M.
Favorite | View/Download:10/0 | TC[WOS]:23 TC[Scopus]:0 | Submit date:2018/11/06
Cardiovascular Protective Agents  Cardiovascular Toxicity  Vascular Insufficiency  Zebrafish Model  
Uptake and protective effects of ergothioneine in human endothelial cells Journal article
Journal of Pharmacology and Experimental Therapeutics, 2014,Volume: 350,Issue: 3,Page: 691-700
Authors:  Li R.W.S.;  Yang C.;  Sit A.S.M.;  Kwan Y.W.;  Lee S.M.Y.;  Hoi M.P.M.;  Chan S.W.;  Hausman M.;  Vanhoutte P.M.;  Leung G.P.H.
Favorite | View/Download:9/0 | TC[WOS]:17 TC[Scopus]:0 | Submit date:2018/11/06
Involvement of organic cation transporter-3 and plasma membrane monoamine transporter in serotonin uptake in human brain vascular smooth muscle cells Journal article
Frontiers in Pharmacology, 2013,Volume: 4 FEB
Authors:  Li R.W.S.;  Yang C.;  Kwan Y.W.;  Chan S.W.;  Lee S.M.Y.;  Leung G.P.H.
Favorite | View/Download:8/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/11/06
Monoamine Transporter  Organic Cation Transporter  Serotonin  Vascular Smooth Muscle Cells  
Enzyme kinetic and molecular docking studies for the inhibitions of miltirone on major human cytochrome P450 isozymes Journal article
Phytomedicine, 2013,Volume: 20,Issue: 2018-03-04,Page: 367
Authors:  Zhou X.;  Wang Y.;  Hu T.;  Or P.M.Y.;  Wong J.;  Kwan Y.W.;  Wan D.C.C.;  Hoi P.M.;  Lai P.B.S.;  Yeung J.H.K.
Favorite | View/Download:7/0 | TC[WOS]:32 TC[Scopus]:0 | Submit date:2018/10/30
Cytochrome P450  Miltirone  Molecular Docking  Probe Substrates  Salvia Miltiorrhiza  
Acute Simvastatin Inhibits KATP Channels of Porcine Coronary Artery Myocytes Journal article
PLoS ONE, 2013,Volume: 8,Issue: 6
Authors:  Seto S.W.;  Au A.L.S.;  Poon C.C.W.;  Zhang Q.;  Li R.W.S.;  Yeung J.H.K.;  Kong S.K.;  Ngai S.M.;  Wan S.;  Ho H.P.;  Lee S.M.Y.;  Hoi M.P.M.;  Chan S.W.;  Leung G.P.H.;  Kwan Y.W.
Favorite | View/Download:10/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/10/30
Effects of Radix Astragali and Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe substrates in pooled human liver microsomes and specific CYP isoforms Journal article
Phytomedicine, 2012,Volume: 19,Issue: 6,Page: 535-544
Authors:  Or P.M.Y.;  Lam F.F.Y.;  Kwan Y.W.;  Cho C.H.;  Lau C.P.;  Yu H.;  Lin G.;  Lau C.B.S.;  Fung K.P.;  Leung P.C.;  Yeung J.H.K.
Favorite | View/Download:13/0 | TC[WOS]:29 TC[Scopus]:0 | Submit date:2019/01/17
Cyp1a2  Cyp2c9  Cyp2d6  Cyp2e1  Cyp3a4  Human Liver Microsomes  Radix Astragali  Radix Rehmanniae  
Metabolism of calycosin, an isoflavone from Astragali Radix, in zebrafish larvae Journal article
Xenobiotica, 2012,Volume: 42,Issue: 3,Page: 294-303
Authors:  Hu G.;  Siu S.O.;  Li S.;  Chu I.K.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.-H.;  Yan R.;  Lee S.M.-Y.
Favorite | View/Download:8/0 | TC[WOS]:28 TC[Scopus]:0 | Submit date:2018/10/30
Calycosin  Conjugation  Isoflavone  Metabolism  Zebrafish Larvae