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Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
Favorite | View/Download:36/0 | TC[WOS]:5 TC[Scopus]:8 | Submit date:2018/10/30
Sodium Tanshinone Iia Sulfonate  Salvia Miltiorrhiza  Hemorrhagic Stroke  Atorvastatin  Rock  
Sichuan pepper attenuates H2O2-induced apoptosis via antioxidant activity and up-regulating heme oxygenase-1 gene expression in primary rat hepatocytes Journal article
JOURNAL OF FOOD BIOCHEMISTRY, 2017,Volume: 41,Issue: 6
Authors:  Zhang, Huan;  Zhou, Xuelin;  Wong, Marcus Ho-Yin;  Man, Ka-Yi;  Pin, Wing-Kwan;  Yeung, John Hok-Keung;  Kwan, Yiu-Wa;  Leung, George Pak-Heng;  Hoi, Pui-Man;  Lee, Simon Ming-Yuen;  Chan, Chi-On;  Mok, Daniel Kam-Wah;  Yu, Peter Hoi-Fu;  Chan, Shun-Wan
Favorite | View/Download:32/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date:2018/10/30
Liver  Reactive Oxygen Species  Rutaceae  Zanthoxylum Bungeanum Maxim  
Evaluation in zebrafish model of the toxicity of rhodamine B-conjugated crotamine, a peptide potentially useful for diagnostics and therapeutics Journal article
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2017,Volume: 31,Issue: 11
Authors:  Chan, Judy Yuet-Wa;  Zhou, Hefeng;  Kwan, Yiu Wa;  Chan, Shun Wan;  Radis-Baptista, Gandhi;  Lee, Simon Ming-Yuen
Favorite | View/Download:51/0 | TC[WOS]:4 TC[Scopus]:6 | Submit date:2018/10/30
Acute Toxicity  Rhodamine B-crotamine  Screening Of Pharmaceuticals  Venom-derived Peptides  Zebrafish Model  
Lysosomal Ca2+ Signaling Regulates High Glucose-Mediated Interleukin-1β Secretion via Transcription Factor EB in Human Monocytic Cells Journal article
PLANT JOURNAL, 2017,Volume: 92,Issue: 3,Page: 452-468
Authors:  Hisa Hui Ling Tseng;  Chi Teng Vong;  Yiu Wa Kwan;  Simon Ming Yuen Lee;  Maggie Pui Man Hoi
Favorite | View/Download:14/0 | TC[WOS]:48 TC[Scopus]:10 | Submit date:2020/05/07
High Glucose  Lysosomal Ca2++++  Ca2++++ Homeostasis  Lysosomal Exocytosis  Interleukin-1β  Monocytes  
Discovery of a ROCK inhibitor, FPND, which prevents cerebral hemorrhage through maintaining vascular integrity by interference with VE-cadherin Journal article
CELL DEATH DISCOVERY, 2017,Volume: 3
Authors:  Shang Li;  Nana Ai;  Mingyun Shen;  Yuanye Dang;  Cheong-Meng Chong;  Peichen Pan;  Yiu Wa Kwan;  Shun Wan Chan;  George Pak Heng Leung;  Maggie Pui Man Hoi;  Tingjun Hou;  Simon Ming-Yuen Lee
Favorite | View/Download:247/0 | TC[WOS]:5 TC[Scopus]:8 | Submit date:2020/01/16
Chemical and pharmacological evaluations on the extract of Scutellaria baicalensis Georgi (Huang-Qin) prepared by various extraction methods Journal article
SpringerPlus, 2016,Volume: 5,Issue: 1
Authors:  Xuelin Zhou;  Pou Seng Choi;  Jia-Ming Yang;  Penelope M. Y. Or;  Pui Man Hoi;  Simon M. Y. Lee;  George P. H. Leung;  Sai Ming Ngai;  Siu Kai Kong;  Ho Pui Ho;  Melody Y. M. Wong;  Shun Wan Chan;  John H. K. Yeung;  Yiu Wa Kwan
Favorite | View/Download:21/0 | TC[WOS]:3 TC[Scopus]:8 | Submit date:2018/11/06
Antioxidant Properties  Extraction Efficiency  Herb–drug Interaction  Scutellaria Baicalensis Georgi  
Antrodia camphorata increases insulin secretion and protects from apoptosis in MIN6 cells Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: MAR
Authors:  Chi Teng Vong;  Hisa Hui Ling Tseng;  Yiu Wa Kwan;  Simon Ming-Yuen Lee;  Maggie Pui Man Hoi
Favorite | View/Download:9/0 | TC[WOS]:4 TC[Scopus]:4 | Submit date:2018/11/06
Antrodia Camphorata  Insulin Secretion  Pancreatic Β-cell Death  Ppar-γ  Type 2 Diabetes Mellitus  
TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Hisa Hui Ling Tseng;  Chi Teng Vong;  Yiu Wa Kwan;  Simon Ming-Yuen Lee;  Maggie Pui Man Hoi
Favorite | View/Download:9/0 | TC[WOS]:20 TC[Scopus]:24 | Submit date:2018/10/30
Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway Journal article
Scientific Reports, 2015,Volume: 5
Authors:  Shang Li;  Yuanye Dang;  Xuelin Zhou;  Bin Huang;  Xiaohui Huang;  Zherui Zhang;  Yiu Wa Kwan;  Shun Wan Chan;  George Pak Heng Leung;  Simon Ming Yuen Lee;  Maggie Pui Man Hoi
Favorite | View/Download:21/0 | TC[WOS]:23 TC[Scopus]:31 | Submit date:2018/11/06
In vitro Vitamin K2 and 1α,25-dihydroxyvitamin D3 combination enhances osteoblasts anabolism of diabetic mice Journal article
European Journal of Pharmacology, 2015,Volume: 767,Page: 30-40
Authors:  Christina C.W. Poon;  Rachel W.S. Li;  Sai Wang Seto;  Siu Kai Kong;  Ho Pui Ho;  Maggie P.M. Hoi;  Simon M.Y. Lee;  Sai Ming Ngai;  Shun Wan Chan;  George P.H. Leung;  Yiu Wa Kwan
Favorite | View/Download:35/0 | TC[WOS]:11 TC[Scopus]:11 | Submit date:2018/11/06
1,25(Oh)2d3  Osteoblasts  Osteoporosis  Type 2 Diabetes Mellitus  Vitamin K2