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Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.;  Getachew R.;  Cao Y.;  Zheng W.;  Osman N.;  Little P.J.
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Multiple growth factors, but not VEGF, stimulate glycosaminoglycan hyperelongation in retinal choroidal endothelial cells Journal article
International Journal of Biological Sciences, 2016,Volume: 12,Issue: 9,Page: 1041-1051
Authors:  Al Gwairi O.;  Osman N.;  Getachew R.;  Zheng W.;  Liang X.-L.;  Kamato D.;  Thach L.;  Little P.J.
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Age related macular degeneration  Bruch's membrane  Growth factors  Proteoglycans  VEGF  Xyloside  
Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response Journal article
Journal of Pharmacy and Pharmacology, 2016,Volume: 68,Issue: 3,Page: 368-378
Authors:  Bernard R.;  Getachew R.;  Kamato D.;  Thach L.;  Osman N.;  Chan V.;  Zheng W.;  Little P.J.
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cell signalling  GAG hyperelongation  platelet derived growth factor  proteoglycan  tinibs  transforming growth factor-β  
The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 8,Page: 956
Authors:  Rostam M.A.;  Kamato D.;  Piva T.J.;  Zheng W.;  Little P.J.;  Osman N.
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Atherosclerosis  Glycosaminoglycan  Signalling  Smad  Transforming growth factor-β  Vascular smooth muscle  
Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 1,Page: 110-119
Authors:  Kamato D.;  Thach L.;  Getachew R.;  Burch M.;  Hollenberg M.D.;  Zheng W.;  Little P.J.;  Osman N.
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Glycosaminoglycan enzymes  Smad linker region  Thrombin  Transactivation-dependent  Transforming growth factor β  
Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling Journal article
British Journal of Pharmacology, 2016,Volume: 173,Issue: 20,Page: 2992-3000
Authors:  Little P.J.;  Hollenberg M.D.;  Kamato D.;  Thomas W.;  Chen J.;  Wang T.;  Zheng W.;  Osman N.
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Peptidyl-prolyl isomerases: Functionality and potential therapeutic targets in cardiovascular disease Journal article
Clinical and Experimental Pharmacology and Physiology, 2015,Volume: 42,Issue: 2,Page: 117-124
Authors:  Rostam M.A.;  Piva T.J.;  Rezaei H.B.;  Kamato D.;  Little P.J.;  Zheng W.;  Osman N.
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Atherosclerosis  Cardiovascular disease  Peptidyl-prolyl isomerase  Pin1  
Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells Journal article
The Journal of pharmacy and pharmacology, 2014,Volume: 66,Issue: 12,Page: 1722-1733
Authors:  Kamato D.;  Rostam M.A.;  Piva T.J.;  Babaahmadi Rezaei H.;  Getachew R.;  Thach L.;  Bernard R.;  Zheng W.;  Little P.J.;  Osman N.
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cell signalling  serine/threonine kinase  Smad linker region  Smads  transforming growth factor-β  
Atherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth muscle Journal article
Cardiovascular Diabetology, 2014,Volume: 13,Issue: 1
Authors:  Al-aryahi S.;  Kamato D.;  Getachew R.;  Zheng W.;  Potocnik S.J.;  Cohen N.;  Guidone D.;  Osman N.;  Little P.J.
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Diabetes  Pleiotropic actions  Smads  Transforming growth factor beta  
Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1055-1063
Authors:  Little P.J.;  Rostam M.A.;  Piva T.J.;  Getachew R.;  Kamato D.;  Guidone D.;  Ballinger M.L.;  Zheng W.;  Osman N.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/21
atherosclerosis  biglycan  imatinib  PDGFβ receptor kinase activity  PDGFβ receptor phosphorylation