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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:258/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:74/0 | TC[WOS]:2 TC[Scopus]:6 | Submit date:2020/09/16
ATM-AMPK-DRP1  BRCA1  inflammasomes  mitochondrial dynamics  mitophagy  
Imaging of macrophage mitochondria dynamics in vivo reveals cellular activation phenotype for diagnosis Journal article
Theranostics, 2020,Volume: 10,Issue: 7,Page: 2897-2917
Authors:  Li,Yue;  He,Yuan;  Miao,Kai;  Zheng,Ying;  Deng,Chuxia;  Liu,Tzu Ming
Favorite | View/Download:79/0 | TC[WOS]:0 TC[Scopus]:4 | Submit date:2020/09/16
In vivo imaging  Liposome  Macrophage  Mitochondria  Multiphoton microscopy  
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun;  Meng,Ya;  Lu,Ligong;  Wang,Chunming;  Liu,Weiwei;  Deng,Chu Xia;  Xu,Ren He;  Chen,Guokai
Favorite | View/Download:72/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Defined factors  Human embryonic stem cells  Keratinocyte differentiation  
Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome Journal article
THERANOSTICS, 2019,Volume: 9,Issue: 13,Page: 3952-3965
Authors:  Dapeng Hao;  Jingjing Li;  Jianlin Wang;  Yuan Meng;  Zhiqiang Zhao;  Chao Zhang;  Kai Miao;  Chuxia Deng;  Benjamin K. Tsang;  Li Wang;  Li-jun Di
Favorite | View/Download:22/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date:2020/05/21
Ovarian Cancer  Estrogen Signaling  Deficiency Of Homologous-recombination  Chemotherapy  Hormone Replacement  
CuS Nanoparticles as a Photodynamic Nanoswitch for Abrogating Bypass Signaling To Overcome Gefitinib Resistance Journal article
NANO LETTERS, 2019,Volume: 19,Issue: 5,Page: 3344-3352
Authors:  Xiajing Gu;  Yuanyuan Qiu;  Miao Lin;  Kai Cui;  Gaoxian Chen;  Yingzhi Chen;  Chenchen Fan;  Yongming Zhang;  Lu Xu;  Hongzhuan Chen;  Jian-Bo Wan;  Wei Lu;  Zeyu Xiao
Favorite | View/Download:14/0 | TC[WOS]:3 TC[Scopus]:6 | Submit date:2020/04/22
Gefitinib  Cus Nanoparticles  Non-small Cell Lung Cancer  Rug Resistance  Active Oxygen Species  
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-G374R mutation in achondroplasia in mice Journal article
Journal of Biological Chemistry, 2019,Volume: 294,Issue: 4,Page: 1142-1151
Authors:  Miao,Kai;  Zhang,Xin;  Su,Sek Man;  Zeng,Jianming;  Huang,Zebin;  Chan,Un In;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:73/0 | TC[WOS]:4 TC[Scopus]:5 | Submit date:2020/09/16
Targeting immune checkpoint B7-H3 antibody-chlorin e6 bioconjugates for spectroscopic photoacoustic imaging and photodynamic therapy Journal article
Chemical Communications, 2019,Volume: 55,Issue: 95,Page: 14255-14258
Authors:  Zhu,Lipeng;  Liu,Jie;  Zhou,Guangyu;  Ng,Hoi Man;  Ang,Irene L.;  Ma,Guofang;  Liu,Yubin;  Yang,Shuo;  Zhang,Fengjuan;  Miao,Kai;  Poon,Terence C.W.;  Zhang,Xuanjun;  Yuan,Zhen;  Deng,Chu Xia;  Zhao,Qi
Favorite | View/Download:72/0 | TC[WOS]:4 TC[Scopus]:5 | Submit date:2020/09/16
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice Journal article
The Journal of Biological Chemistry, 2018
Authors:  Kai Miao;  Xin Zhang;  Sek Man Su;  Jianming Zeng;  Zebin Huang;  Un In Chan;  Xiaoling Xu;  Chu-Xia Deng
Favorite | View/Download:35/0 | TC[WOS]:0 TC[Scopus]:5 | Submit date:2018/12/17
Fgfr3  Crispr/cas9  Protein  Targeted Correction  Off-target  Achondroplasia  Dwarfism  Genome Editing  Gene Therapy  
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy Journal article
Human molecular genetics, 2018
Authors:  Xiaoling Xu;  Eric Chen;  Lihua Mo;  Lei Zhang;  Fangyuan Shao;  Kai Miao;  Jianlin Liu;  Sek Man Su;  Monica Valecha;  Un In Chan;  Hongping Zheng;  Mark Chen;  Weiping Chen;  Qiang Chen;  Haiqing Fu;  Mirit I. Aladjem;  Yanzhen He;  Chu-Xia Deng
Favorite | View/Download:45/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2018/12/17