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BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite  |  View/Download:11/0  |  Submit date:2018/12/17
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space Journal article
PLOS GENETICS, 2018,Volume: 14,Issue: 3
Authors:  Veri, Amanda O.;  Miao, Zhengqiang;  Shapiro, Rebecca S.;  Tebbji, Faiza;  O'Meara, Teresa R.;  Kim, Sang Hu;  Colazo, Juan;  Tan, Kaeling;  Vyas, Valmik K.;  Whiteway, Malcolm;  Robbins, Nicole;  Wong, Koon Ho;  Cowen, Leah E.
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A Journal article
CANCER LETTERS, 2018,Volume: 436,Page: 28-37
Authors:  Liu, Yifan;  Yang, Eun Ju;  Zhang, Baoyuan;  Miao, Zhengqiang;  Wu, Changjie;  Lyu, Junfang;  Tan, Kaeling;  Poon, Terence Chuen Wai;  Shim, Joong Sup
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Akt  Kw2449  Synthetic Lethality  Aurka  Drug Combination  
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation Journal article
NATURE COMMUNICATIONS, 2017,Volume: 8
Authors:  Xie, Jinglin L.;  Qin, Longguang;  Miao, Zhengqiang;  Grys, Ben T.;  Diaz, Jacinto De La Cruz;  Ting, Kenneth;  Krieger, Jonathan R.;  Tong, Jiefei;  Tan, Kaeling;  Leach, Michelle D.;  Ketela, Troy;  Moran, Michael F.;  Krysan, Damian J.;  Boone, Charles;  Andrews, Brenda J.;  Selmecki, Anna;  Wong, Koon Ho;  Robbins, Nicole;  Cowen, Leah E.
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodeling and chromatin architecture in Candida albicans Journal article
NATURE COMMUNICATIONS, 2016,Volume: 7
Authors:  Michelle D. Leach;  Rhys A. Farrer;  Kaeling Tan;  Zhengqiang Miao;  Louise A. Walker;  Christina A. Cuomo;  Robert T. Wheeler;  Alistair J. P. Brown;  Koon Ho Wong;  Leah E. Cowen
Favorite  |  View/Download:1/0  |  Submit date:2019/01/21
Genome-wide transcriptional regulation and chromatin dynamics in response to nitrogen availability in Aspergillus nidulans Conference paper
28th Fungal Genetics Conference, Pacific Grove, CA, March 17-22, 2015
Authors:  Damien J. Downes;  Zhengqiang Miao;  Djordje Djordjevic;  Vinita Deshpande;  Ang Li;  Kaeling Tan;  Grethel Y Busot;  Joshua W.K. Ho;  Richard B. Todd;  Koon Ho Wong
Favorite  |  View/Download:3/0  |  Submit date:2019/01/31
SCFcdc4-mediated Degradation of the Hac1p Transcription Factor Regulates the Unfolded Protein Response in Saccharomyces cerevisiae Journal article
Molecular biology of the cell, 2007,Volume: 18,Issue: 2,Page: 426-440
Authors:  Bhupinder Pal;  Nickie C. Chan;  Leon Helfenbaum;  Kaeling Tan;  William P. Tansey;  Mary-Jane Gething
Favorite  |  View/Download:2/0  |  Submit date:2019/01/29
Molecular characterization of hepatitis B virus surface antigen mutants in Singapore patients with hepatocellular carcinoma and hepatitis B virus carriers negative for HBsAg but positive for anti-HBs Journal article
Journal of Gastroenterology and Hepatology, 2002,Volume: 17,Page: S491-S496
Authors:  CHONG JIN OON;  WEI NING CHEN;  KEE TAI GOH;  STEVEN MESENAS;  HAN SEONG NG;  GILBERT CHIANG;  CLARENCE TAN;  SHIUAN KOH;  SIAW WEI TENG;  IVY TOH;  MEI CHUNG MOH;  KIAN SIM GOO;  KAELING TAN;  AI LIN LEONG AND;  GEK SAN TAN
Favorite  |  View/Download:1/0  |  Submit date:2019/01/29
Hepatitis b  Hepatoma  Seronegative  Suface Mutants