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Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice Journal article
The Journal of Biological Chemistry, 2018
Authors:  Kai Miao;  Xin Zhang;  Sek Man Su;  Jianming Zeng;  Zebin Huang;  Un In Chan;  Xiaoling Xu;  Chu-Xia Deng
Favorite  |  View/Download:14/0  |  Submit date:2018/12/17
Fgfr3  Crispr/cas9  Protein  Targeted Correction  Off-target  Achondroplasia  Dwarfism  Genome Editing  Gene Therapy  
Deficiency in Fpr2 results in reduced numbers of Lin(-)cKit(+)Sca1(+) myeloid progenitor cells Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 35,Page: 13452-13463
Authors:  Chen, Keqiang;  Singh, Vijay K.;  Tang, Peng;  Bao, Zhiyao;  He, Tianzhen;  Xiang, Yi;  Gong, Wanghua;  Yoshimura, Teizo;  Le, Yingying;  Tessarollo, Lino;  Chen, Xin;  Wang, Ji Ming
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
mouse  bone marrow  myeloid cell  proliferation  cytokine  c-KIT  Fpr2  Lin(-)c-Kit(+)Sca1(+)cells  SCF  
Deficiency in Fpr2 results in reduced numbers of Lin− cKit+ Sca1+ myeloid progenitor cells Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 42,Page: 16175-16175
Authors:  Keqiang Chen;  Vijay K. Singh;  Peng Tang;  Zhiyao Bao;  Tianzhen He;  Yi Xiang;  Wanghua Gong;  Teizo Yoshimura;  Yingying Le;  Lino Tessarollo;  Xin Chen;  Ji Ming Wang
Favorite  |  View/Download:3/0  |  Submit date:2019/01/14
Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 22,Page: 8315-8329
Authors:  Sun, Heng;  Miao, Zhengqiang;  Zhang, Xin;  Chan, Un In;  Su, Sek Man;  Guo, Sen;  Wong, Chris Koon Ho;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Mammary Gland  Development  Breast Cancer  Biomarker  Cell Differentiation  Stem Cells  cdh5+cell  Mammary Stem Cells (Mascs)  Single Cell Rna-seq  
An efficient platform for generating somatic point mutations with germline transmission in the zebrafish by CRISPR/Cas9-mediated gene editing Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 17,Page: 6611-6622
Authors:  Yibo Zhang;  Zhiwei Zhang;  Wei Ge
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
Somatic Point Mutation  Crispr/cas9  Homology-directed Recombination (Hdr)  Knock-in  Zebrafish  
Structural insights into ankyrin repeat-mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 6,Page: 1944-1956
Authors:  Pan, Wenfei;  Sun, Kang;  Tang, Kun;  Xiao, Qingpin;  Ma, Chenxue;  Yu, Cong;  Wei, Zhiyi
Favorite  |  View/Download:5/0  |  Submit date:2018/10/30
crystal structure  focal adhesion  protein complex  scaffold protein  tumor suppressor gene  KANK  ankyrin repeat  
DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor B are not correlated Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017,Volume: 292,Issue: 46,Page: 18821-18830
Authors:  Mulero, Maria Carmen;  Huang, De-Bin;  Thien Nguyen, H.;  Wang, Vivien Ya-Fan;  Li, Yidan;  Biswas, Tapan;  Ghosh, Gourisankar
Favorite  |  View/Download:5/0  |  Submit date:2018/10/30
cooperativity  crystal structure  dimerization  DNA transcription  NF-kB transcription factor  E-selectin  RelA  kB site  
SMAD3 Regulates follicle-stimulating hormone synthesis by pituitary gonadotrope cells in vivo Journal article
Journal of Biological Chemistry, 2017,Volume: 292,Issue: 6,Page: 2301-2314
Authors:  Li Y.;  Schang G.;  Boehm U.;  Deng C.-X.;  Graff J.;  Bernard D.J.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/13
DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor κb are not correlated Journal article
Journal of Biological Chemistry, 2017,Volume: 292,Issue: 46,Page: 18821-18830
Authors:  Mulero M.C.;  Huang D.-B.;  Thien Nguyen H.;  Wang V.Y.-F.;  Li Y.;  Biswas T.;  Ghosh G.
Favorite  |  View/Download:4/0  |  Submit date:2019/01/15
Structure and function of Cross-class complexes of G Protein-Coupled secretin and angiotensin 1a receptors Journal article
Journal of Biological Chemistry, 2016,Volume: 291,Issue: 33,Page: 17332-17344
Authors:  Harikumar K.G.;  Augustine M.L.;  Lee L.T.O.;  Chow B.K.C.;  Miller L.J.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/15