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Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite  |  View/Download：6/0  |  Submit date：2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells Journal article
FOOD AND CHEMICAL TOXICOLOGY, 2019,Volume: 131
Authors:  Mu-Yang Huang;  Xiao-Ming Jiang;  Yu-Lian Xu;  Luo-Wei Yuan;  Yu-Chi Chen;  Guozhen Cui;  Run-Yue Huang;  Bo Liu;  Yitao Wang;  Xiuping Chen;  Jin-Jian Lu
Favorite  |  View/Download：9/0  |  Submit date：2019/11/22
Programmed Death Ligand-1  Platycodin d  Extracellular Release  Natural Products  Cancer  
γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 363,Page: 142-153
Authors:  Wang A.;  Zhou F.;  Li D.;  Lu J.-J.;  Wang Y.;  Lin L.
Favorite  |  View/Download：11/0  |  Submit date：2018/12/28
Fibrogenesis  Hmgb1  Liver Fibrosis  Sirtuin 3  Superoxide  Γ-mangostin  
Nagilactone E suppresses TGF-β1-induced epithelial–mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
Phytomedicine, 2019,Volume: 52,Page: 32-39
Authors:  Zhang L.-L.;  Jiang X.-M.;  Huang M.-Y.;  Feng Z.-L.;  Chen X.;  Wang Y.;  Li H.;  Li A.;  Lin L.-G.;  Lu J.-J.
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Epithelial-mesenchymal transition  Nagilactone E  Smad  TGF-β1  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
Favorite  |  View/Download：6/0  |  Submit date：2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
Inhibition of lung cancer by 2-methoxy-6-acetyl-7-methyljuglone (MAM) through induction of necroptosis by targeting receptor-interacting protein 1 (RIP1) Journal article
Antioxidants & Redox Signaling, 2018,Volume: 0,Issue: JA
Authors:  Sun W;  Yu J;  Gao H;  Wu X;  Wang S;  Hou Y;  Lu JJ;  Chen X
Favorite  |  View/Download：6/0  |  Submit date：2019/01/16
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation Journal article
Apoptosis, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Cao W.-X.;  Li T.;  Tang Z.-H.;  Zhang L.-L.;  Wang Z.-Y.;  Guo X.;  Su M.-X.;  Chen X.;  Lu J.-J.
Favorite  |  View/Download：5/0  |  Submit date：2018/12/28
Apoptosis  Chelerythrine  Eif2α  Mlkl  Ros  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download：497/30  |  Submit date：2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
The bone-protecting efficiency of Chinese medicines compared with Western medicines in rheumatoid arthritis: A systematic review and meta-analysis of comparative studies Journal article
Frontiers in Pharmacology, 2018,Volume: 9,Issue: AUG
Authors:  Cai X.;  Chen X.-M.;  Xia X.;  Bao K.;  Wang R.-R.;  Peng J.-H.;  Liu H.-J.;  Yang Q.-W.;  Yan J.-Y.;  Wang M.-J.;  Yu H.;  Lu J.-J.;  Hu Y.-J.;  Jakobsson P.-J.;  Wen Z.-H.;  Huang R.-Y.;  Huang Q.-C.
Favorite  |  View/Download：5/0  |  Submit date：2018/12/28
Bone-protecting Efficiency  Chinese Medicine  Meta-analysis  Rheumatoid Arthritis (Ra)  Systematic Review  
A novel design of a polynuclear co-delivery system for safe and efficient cancer therapy Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 63,Page: 8737-8740
Authors:  Xing, Lei;  Zhang, Jia-Liang;  Zhou, Tian-Jiao;  He, Yu-Jing;  Cui, Peng-Fei;  Gong, Jia-Hui;  Sun, Minjie;  Lu, Jin-Jian;  Huang, Zhangjian;  Jin, Liang;  Jiang, Hu-Lin
Favorite  |  View/Download：16/0  |  Submit date：2018/10/30