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Divergence of anti-angiogenic activity and hepatotoxicity of different stereoisomers of itraconazole Journal article
Clinical Cancer Research, 2016,Volume: 22,Issue: 11,Page: 2709-2720
作者:  Joong Sup Shim;  Ruo-Jing Li;  Namandje N. Bumpus;  Sarah A. Head;  Kalyan Kumar;  Eun Ju Yang;  Junfang Lv;  Wei Shi;  Jun O. Liu
收藏  |  浏览/下载:2/0  |  提交时间:2019/01/24
Itraconazole  Stereoisomers  Drug Repositioning  Angiogenesis  Hepatotoxicity  
Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2015,Volume: 112,Issue: 52,Page: E7276
作者:  Head S.A.;  Shi W.;  Zhao L.;  Gorshkov K.;  Pasunooti K.;  Chen Y.;  Deng Z.;  Li R.-J.;  Shim J.S.;  Tan W.;  Hartung T.;  Zhang J.;  Zhao Y.;  Colombini M.;  Liu J.O.
收藏  |  浏览/下载:8/0  |  提交时间:2018/10/30
Angiogenesis  Itraconazole  Metabolism  Mitochondria  VDAC1  
The antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015,Volume: 112,Issue: 52,Page: E7276-E7285
作者:  Sarah A. Head;  Wei Shi;  Liang Zhao;  Kirill Gorshkov;  Kalyan Pasunooti;  Yue Chen;  Zhiyou Deng;  Ruo-jing Li;  Joong Sup Shim;  Wenzhi Tan;  Thomas Hartung;  Jin Zhang;  Yingming Zhao;  Marco Colombini;  Jun O. Liu
收藏  |  浏览/下载:5/0  |  提交时间:2019/01/24
Angiogenesis  Mitochondria  Metabolism  Itraconazole  Vdac1