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Development of Natural Product-Conjugated Metal Complexes as Cancer Therapies Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019,Volume: 20,Issue: 2
Authors:  Ma, DL;  Wu, C;  Cheng, SS;  Lee, FW;  Han, QB;  Leung, CH
Favorite  |  View/Download:4/0  |  Submit date:2020/03/24
Cancer Therapy  Cytotoxicity  Natural Product  Transition Metal Complex  
Emerging Screening Approaches in the Development of Nrf2-Keap1 Protein-Protein Interaction Inhibitors Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019,Volume: 20,Issue: 18
Authors:  Leung, CH;  Zhang, JT;  Yang, GJ;  Liu, H;  Han, QB;  Ma, DL
Favorite  |  View/Download:5/0  |  Submit date:2020/03/23
Virtual Screening  Keap1-nrf2  Protein-protein Interaction  Inhibitors  Oxidative Stress  
A hybrid cuckoo search and differential evolution approach to protein–ligand docking Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 10
Authors:  Lin H.;  Siu S.W.I.
Favorite  |  View/Download:4/0  |  Submit date:2019/04/04
Autodock vina  Conformational search  Cuckoo search  CuckooVina  Differential evolution  Metaheuristic  Optimization  PSOvina  Structure-based drug design  
aP2-Cre mediated ablation of GHS-R attenuates adiposity and improves insulin sensitivity during aging Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 10
Authors:  Lin L.;  Lee J.H.;  Wang R.;  Wang R.;  Sheikh-Hamad D.;  Zang Q.S.;  Sun Y.
Favorite  |  View/Download:8/0  |  Submit date:2019/01/15
Adipose Tissues  Ghrelin  Ghs-r  Thermogenesis  Tissue-specific Knockdown Mice  Ucp1  
Tanshinone IIA attenuates insulin like growth factor 1-induced cell proliferation in PC12 cells through the PI3K/Akt and MEK/ERK pathways Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 9
Authors:  Wang H.;  Su X.;  Fang J.;  Xin X.;  Zhao X.;  Gaur U.;  Wen Q.;  Xu J.;  Little P.J.;  Zheng W.
Favorite  |  View/Download:17/0  |  Submit date:2018/12/21
Akt  Antiproliferation  ERK  IGF-1R  Tanshinone IIA  
Application of Nanoparticles for Targeting G Protein-Coupled Receptors Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018,Volume: 19,Issue: 7
Authors:  Ma, Xin;  Xiong, Yunfang;  Lee, Leo Tsz On
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
g Protein-coupled Receptor (Gpcr)  Cancer  Nanoparticles (Nps)  Dendrimers  Quantum Dots (Qds)  Gold Nanoparticles (Aunps)  Magnetic Nanoparticles (Mnps)  
Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
Berberine protects human retinal pigment epithelial cells from hydrogen peroxide-induced oxidative damage through activation of AMPK Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Li S.;  Gaur U.;  Chong C.-M.;  Lin S.;  Fang J.;  Zeng Z.;  Wang H.;  Zheng W.
Favorite  |  View/Download:9/0  |  Submit date:2018/12/21
Age-related macular degeneration  AMPK  Berberine  D407 cells  
Berberine Protects Human Retinal Pigment Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Damage through Activation of AMPK Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018,Volume: 19,Issue: 6
Authors:  Li, Shuai;  Gaur, Uma;  Chong, Cheong-Meng;  Lin, Shaofen;  Fang, Jiankang;  Zeng, Zhiwen;  Wang, Haitao;  Zheng, Wenhua
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Berberine  Age-related Macular Degeneration  D407 Cells  Ampk  
Silencing stem cell factor gene in fibroblasts to regulate paracrine factor productions and enhance c-Kit expression in melanocytes on melanogenesis Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 5
Authors:  Li P.-H.;  Liu L.-H.;  Chang C.-C.;  Gao R.;  Leung C.-H.;  Ma D.-L.;  David Wang H.-M.
Favorite  |  View/Download:7/0  |  Submit date:2018/11/06
Fibroblasts  Melanin  Melanocytes  Paracrine Factors  Stem Cell Factor