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IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells Journal article
FASEB Journal, 2015,Volume: 29,Issue: 2,Page: 443-454
Authors:  Chen X.;  Willette-Brown J.;  Wu X.;  Hu Y.;  Howard O.M.Z.;  Hu Y.;  Oppenheim J.J.
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Colitis  Foxp3  Lymphopenic Mouse  Proliferation  
The alarmin HMGN1 contributes to antitumor immunity and is a potent immunoadjuvant Journal article
Cancer Research, 2014,Volume: 74,Issue: 21,Page: 5989-5998
Authors:  Wei F.;  Yang D.;  Tewary P.;  Li Y.;  Li S.;  Chen X.;  Howard O.M.Z.;  Bustin M.;  Oppenheim J.J.
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In vitro generated Th17 cells support the expansion and phenotypic stability of CD4+Foxp3+ regulatory T cells in vivo Journal article
Cytokine, 2014,Volume: 65,Issue: 1,Page: 56-64
Authors:  Zhou Q.;  Hu Y.;  Howard O.M.Z.;  Oppenheim J.J.;  Chen X.
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Il-2  Regulatory t Cell  Th17  Tnf  Tnfr2  
TNFR2 is critical for the stabilization of the cd4+foxp3+ regulatory t cell phenotype in the inflammatory environment Journal article
Journal of Immunology, 2013,Volume: 190,Issue: 3,Page: 1076-1084
Authors:  Chen X.;  Wu X.;  Zhou Q.;  Howard O.M.Z.;  Netea M.G.;  Oppenheim J.J.
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Expression of costimulatory TNFR2 induces resistance of CD4 +FoxP3- conventional T cells to suppression by CD4 +FoxP3+ regulatory T cells Journal article
Journal of Immunology, 2010,Volume: 185,Issue: 1,Page: 174-182
Authors:  Chen X.;  Hamano R.;  Subleski J.J.;  Hurwitz A.A.;  Howard O.M.Z.;  Oppenheim J.J.
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Co-expression of TNFR2 and CD25 identifies more of the functional CD4 +FOXP3+ regulatory T cells in human peripheral blood Journal article
European Journal of Immunology, 2010,Volume: 40,Issue: 4,Page: 1099-1106
Authors:  Chen X.;  Subleski J.J.;  Hamano R.;  Howard O.M.Z.;  Wiltrout R.H.;  Oppenheim J.J.
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Cd25  Human Regulatory t Cells  Peripheral Blood  Tnfr2  
Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells Journal article
International Immunopharmacology, 2007,Volume: 7,Issue: 13,Page: 1819-1824
Authors:  Kopf H.;  de la Rosa G.M.;  Howard O.M.Z.;  Chen X.
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cd4+cd25+foxp3+ t Regulatory Cells  Rapamycin  Th17 Cells  
Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells Journal article
Biochemical and Biophysical Research Communications, 2007,Volume: 362,Issue: 1,Page: 44-50
Authors:  Kim J.-Y.;  Kim H.-J.;  Hurt E.M.;  Chen X.;  Howard O.M.Z.;  Farrar W.L.
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Foxp3  Jurkat-t Cells  Transduction  Treg  
Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells Journal article
Journal of Immunology, 2007,Volume: 179,Issue: 1,Page: 154-161
Authors:  Chen X.;  Baumel M.;  Mannel D.N.;  Howard O.M.Z.;  Oppenheim J.J.
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Pertussis toxin by inducing IL-6 promotes the generation of IL-17-producing CD4 cells Journal article
Journal of Immunology, 2007,Volume: 178,Issue: 10,Page: 6123-6129
Authors:  Chen X.;  Howard O.M.Z.;  Oppenheim J.J.
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